Chemicals & Materials

Rx for Pharma

Critical Issues
Girish Malhotra, P.E.
Chemical engineers could hold the key that helps pharmaceutical companies — facing pressure to control rising drug prices and competition from generics — reduce their manufacturing costs.

Fermentation Goes Large-Scale

Special Section
Alex Patist, J. J. Hahn , Aristos Aristidou , Pim van Hoek
Designing an economically competitive and environmentally sustainable fermentation route means considering the downstream separations needed to capture the final product during the initial process design.

Innovations in Food Processing

Fluids and Solids Handling
B. G. Swanson, M. F. San Martín, G. V.  Barbosa-Cánovas
Today's savvy consumers want processed foods to look freshly prepared, while still meeting all safety requirements. Conventional thermal treatments are inadequate to fulfill this demand. New nonthermal techniques, such as pulsed-electric fields, are...

Selecting Agitator Seals for Bioprocessing Applications

Fluids and Solids Handling
William Ho Liam Teng, Gregory T. Benz
Issues such as sterility, isolation and contamination must be considered when choosing seals for use in biotech and pharmaceutical processes. This overview describes common types of seals and offers guidance on selecting the appropriate seal for...

Choose Materials for High-Temperature Environments

Peter  Elliott
High temperatures, stresses, and the presence of elements such as oxygen, sulfur, or the halogens can add up to trouble. Here is how to screen candidate alloys for such service.

Nano-technology: Fueling the Chemical Industry's Future

Special Section
Mihail C. Roco, Mindy Rittner, Daniela L. Carrillo, Paul Holister, Cristina Roman Vas, Tim Harper
Nanotechnology, as a whole, is still an emerging area with the need to make progress in both scientific and technological terms before enormous commercialization of products may occur. Nevertheless, commercial products are out there — more in some...

Bioreactor Design for Chemical Engineers

Back To Basics
Gregory T. Benz
Fermentation processes are based on chemical engineering principles. Understand these concepts to achieve optimal bioreactor design.

Designing a Facility for API Development

Plant Design
Yasha Zelmanovich, Terrence Fay
Kilo labs are instrumental in scaling up the production of active pharmaceutical ingredients. This article discusses the critical factors that must be considered to design such a facility.

Exploring New Paradigms for Bioprocessing

SBE Special Section
Jonathan Monk
Disruptive technologies, such as disposable bioreactors, metabolic ?ux models, and glycoengineered yeast, could change the face — and pace — of biomanufacturing.

Good Drug Therapy: It's Not Just the Molecule - It's the DELIVERY

Special Section
Rita D'Aquino
In today's competitive marketplace, biopharmaceutical companies are seeking effective and user-friendly drug-delivery platforms for their drug molecules. Miniaturized, microfabricated and nanofabricated devices that can be implanted in the body are...

Choose the Right Elastomer

William M. Stahl
Match a material's performance to process conditions to reduce leaks, improve safety and extend the mean time between failures (MTBF).

Keys to Bioreactor Selection

Reactions and Separations
John A. Williams
A few basic types of bioreactor designs are used to produce a wide range of products, from antibiotics to foods to fuels. Here's how to pick the best options for your application.

Chemical Engineering in the Pharmaceutical Industry: R&D to Manufacturing

October, 2010
This book deals with various unique elements in the drug development process within chemical engineering science and pharmaceutical R&D. The book is intended to be used as a professional reference and potentially as a text book reference in pharmaceutical engineering and pharmaceutical sciences...

Hydrogen and Syngas Production and Purification Technologies

December, 2009
Covers the timely topic of fuel cells and hydrogen-based energy from its fundamentals to practical applications Serves as a resource for practicing researchers and as a text in graduate-level programs Tackles crucial aspects in light of the new directions in the energy industry, in particular how...

Handbook of Polymer Solution Thermodynamics

December, 1993
Created for engineers and students working with pure polymers and polymer solutions, this handbook provides up-to-date, easy to use methods to obtain specific volumes and phase equilibrium data. A comprehensive database for the phase equilibria of a wide range of polymer-solvent systems, and PVT...
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