Chemical Engineering Practice

Fulfilling the Promise of Nanomedicine

February
2006
SBE Special Section
Rita D'Aquino with Tim Harper, Cristina Roman Vas
Leveraging nanotechnology in the life science industries has given scientists new tools with which they have the potential to transform the world of medicine.

Developing Crystallization Processes

March
2011
Reactions and Separations
Christianto Wibowo
With solid-liquid equilibrium as its foundation, this systematic approach makes it easy to identify operating regions and theoretical yield to maximize the desired product.

Selecting Sensors for Safety Instrumented Systems

July
2015
Back To Basics
Jessica Lo, Erik Mathiason, Chad McGuire
A plant’s safety instrumented system (SIS) is critical in preventing process safety incidents. Use this guide to help choose the proper sensors for your plant’s SIS.

Crystallization Operations

Public (classroom) Course
A practical overview of the basics of crystallization and precipitation and how to apply the fundamentals of crystal growth and nucleation to...

Producing Nitrogen via Pressure Swing Adsorption

June
2012
Reactions and Separations
Svetlana Ivanova, Robert Lewis
Pressure swing adsorption (PSA) can be a cost-effective method of onsite nitrogen generation for a wide range of purity and flow requirements.

Best Practices for Pilot-Plant Piping

April
2014
Fluids and Solids Handling
Richard Palluzi
Pilot-plant piping is subject to more-frequent modification than typical process plant piping, and must be able to accommodate a range of media, temperatures, and pressures during its lifetime. Use this guide to determine which piping, tubing, and fittings are optimal for your pilot plant application.

Predict Incidents with Process Safety Performance Indicators

February
2016
Safety
Wahid Azizi
Become a seer of process safety incidents with carefully chosen process safety performance indicators (PSPIs). A PSPI program developed using the barrier-based or tier-based approach will serve as your crystal ball.

Basic Emergency Relief System Design

Public (classroom) Course
Preparing to use DIERS technology in your emergency relief system design - but not sure where to start? Attend this instructor-led, 3-day course for...

Understand Flow Patterns in Glass-Lined Reactors

November
2004
Reactions and Separations
Kevin J. Bittorf, David S. Dickey, Keith E. Johnson , Christopher J. Ramsey
Physical modeling and computer simulation provide insights into the performance of a glass-lined reactor.

Safely Handle Powdered Solids

December
2005
Fluids and Solids Handling
Stanley S. Grossel, Russell Kahn, Daniel E. Silva, Robert Zalosh
Understand some of the accident scenarios that result in dust explosions, and follow these suggestions for preventing them.

Environmental Law for Chemical Engineers

February
2012
Back To Basics
Mary Ellen Ternes
A basic understanding of environmental law is beneficial for all chemical engineers. Learn how laws are proposed, made, and implemented, and ways to avoid incurring unnecessary penalties.

Calculate Financial Indicators to Guide Investments

September
2013
Back To Basics
John Anderson, Andy Fennell
Engineers can become better informed about their work with an increased familiarity of basic financial indicators. Use these insights to help ensure that the projects you work on are those that are most likely to become financial successes.

Modeling Chemical Reactors

February
2015
Reactions and Separations
Ed Fontes
Models can be used to describe chemical reactors to help solve problems and optimize processes, while saving time, money, and resources.

Determining Manufacturing Costs

January
2009
Back To Basics
John Anderson
Making early estimates of a product's cost components enables developers to manage resources wisely and evaluate the product's economic viability.

Excel VBA Programming for Chemical Engineers

Public (classroom) Course
Get up-to-date on proven design and troubleshooting principles for handling bulk solids in bins, hoppers, chutes and feeders for safe and trouble-...

Real World Modeling of Distillation

July
2003
Reactions and Separations
Harry Kooijman, Rajamani Krishna , Ross Taylor
Previously, simulations based on nonequilibrium, or rate-based, models were considered impractical due to their complexity. However, with ever-increasing computing power, these simulations are not only feasible, but in some circumstances they should...

Evaluating Distillation Column Performance

June
2013
Reactions and Separations
AIChE’s Equipment Testing Procedures Committee, Tray and Packed Columns Procedure Revision Subcommittee
Follow these guidelines to assess the capacity and efficiency of distillation columns containing trays or packing.

Applications in Drug Delivery and Tissue Engineering

February
2006
SBE Special Section
Ali Khademosseini, Robert Langer
Nanotechnology is an emerging field that could potentially make a major impact on human health. Nanomaterials promise to revolutionize medicine and are increasingly used in drug delivery or tissue engineering applications.

Apply Six Sigma for Process Improvement and Problem-Solving

March
2011
Back To Basics
George Liebermann
Many manufacturing processes are not run as efficiently as they could be. The Six Sigma methodology provides a foundation for continuous improvement and for solving quality, operational, and other problems.

Understand Advanced Process Control

June
2016
Back To Basics
Perry Nordh, P.Eng.
Multivariable processes are controlled by a hierarchical structure of control layers. Field devices and regulatory controls manage individual variables, while advanced process control and production control systems coordinate multiple variables to optimize operation.

Pneumatic Conveying of Bulk Solids

eLearning (online) Course
Learn design and troubleshooting strategies that result in trouble-free flow. This online course addresses challenges like wear, attrition, rate...

Design Reactors via CFD

December
2001
Reactions and Separations
Ahmad H. Haidari, Andre Bakker, Elizabeth M. Marshall
Using computational fluid dynamics to design commercial-size batch and continuous reactors can eliminate subjective experience and empiricism, leading to better-designed, more-efficient units.

Nuclear Renaissance: A Flawed Proposition

July
2010
Special Section
Anthony D'Agostino, Benjamin K. Sovacool
Nuclear power has never been safe and it never will be. Efficiency gains and investment in renewable sources of energy will be sufficient to power the planet without resorting to nuclear reactors.

CEP: Editorial - More Than a Spoonful of Sugar

March
2013
Editorial
Cynthia Mascone
Many of us remember receiving our polio vaccine on a sugar cube. Indeed, that was the motivation behind A Spoonful of Sugar, a song from the classic Disney movie Mary Poppins. Walt Disney had instructed the Sherman brothers, Robert and Richard, to come up with a catchy song for the film. When Robert arrived at home, after working all day trying to come up with an idea, his wife told him that the children had gotten their polio vaccine that day. Thinking they had gotten a shot, he asked them if it hurt. His son answered that the medicine was put on a cube of sugar and he swallowed it. And so “a spoonful of sugar helps the medicine go down was born.

Designing Polymerization Reaction Systems

February
2016
Reactions and Separations
Shrikant Dhodapkar, Pradeep Jain, Carlos Villa
Important considerations in polymerization reactor design include heat removal, kinetics, and process dynamics, as well as polymer properties and product quality.

SAChE证书课程–氮在过程安全的作用

eLearning (online) Course
这门SAChE安全证书课程重点讲化学工业中的基本物质-氮气。因为是惰性气体,氮气在化工生产、加工、处理和运输等各个方面有着广泛的应用。氮封使可燃物的安全储存和使用成为可能,还有助于防止可燃粉尘爆炸。但是,它也是一个明显的窒息性气体,在其处理和使用中必须应用安全原则。

Improve Solids Handling During Thermal Drying

November
2004
Fluids and Solids Handling
John W. Carson, Herman Purutyan, Thomas G. Troxel
Follow these guidelines for ensuring the proper flow of slurries, pastes and wet powders to achieve a dried product with the desired characteristics.

Green Reactors

August
2008
Reactions and Separations
Mukesh Doble
Compare these microreactor technologies, along with the intrinsic advantages and disadvantages of miniaturization, to achieve process intensification.

Video Tutorial: Intro to Cascade Control

July 14, 2016
Wondering when cascade control is best used? Learn about its advantages and understand when cascade control presents disadvantages. This video tutorial will also look at the block...

Pneumatic Conveying of Bulk Solids

Public (classroom) Course
Gain a better understanding of pneumatic conveying problems and principles, allowing you to evaluate and troubleshoot your in-plant systems to...

Streamlining Crystallization Process Design

January
2004
Fluids and Solids Handling
Christianto  Wibowo, Lionel O'Young, Ka M. Ng
Use phase diagrams to develop reliable crystallization processes quickly and cost effectively.

Process Safety Beacon: Understand Chemical Compatibility

July
2016
Process Safety Beacon
Chemical compatibility charts can be used to determine the chemical reactivity of thousands of common hazardous chemicals, the compatibility of absorbents, and the suitability of materials of construction in chemical processes.

Integrated Process Synthesis

Public (classroom) Course
As a chemical engineer, before you can make proposed process alterations you must consider the potential investment return. Yet, typically this...

Piloting Bioreactors for Agitation Scale-Up

February
2008
Reactions and Separations
Gregory T. Benz
This article offers guidance on how to design appropriate experiments to measure scalable data for agitation in both aerobic and anaerobic bioreactors.

Nanosensors: Evolution, Not Revolution...Yet

June
2008
News Feature
Suzanne A. Shelley
Promising nanotechnology-enabled sensors, monitoring devices and analytical instruments continue to advance toward commercialization for diverse industrial, environmental, medical and military applications— but hurdles remain.

Choose the Right Gas Sensor

September
2009
Instrumentation
Sandra Barnes
Selecting a sensor for continuous monitoring involves many considerations. This article discusses the types of sensors available, their applicability and limitations, and how to choose an appropriate sensor to protect people and equipment.

CEP: Process Automation Corner - Process Simulation and Process Control

September
2013
Process Automation Corner
Terry McMahon
Chemical engineers have been practicing process simulation since the advent of the profession in the early 20th century. It was called process design and inevitably involved simplifying assumptions, including that steady-state process conditions had...

Determining Discharge Rates of Particulate Solids

May
2016
Fluids and Solids Handling
Shrikant Dhodapkar, Karl V. Jacob, Madhusudhan Kodam
Many factors affect the flowrate of bulk solids. This article reviews the underlying physics of solids flow and explains how to calculate the discharge rate of solids from processing and handling equipment.

Modeling Reactive Absorption

January
2009
Reactions and Separations
Eugeny Kenig, Panos Seferlis
Effective modeling of reactive absorption enhances system design, improves experiment planning for parameter-estimation, and facilitates process operation and control decisions.

SBE Special Section: Biopharmaceuticals - Continuous Processing in Upstream Operations

December
2015
SBE Special Section
Chun Chen, Chetan T. Goudar, Huong Le
Perfusion technology offers many benefits over fed-batch processing, such as reducing the size of the bioreactor, which reduces capital costs and enables the use of single-use bioreactor technology. Despite these advantages, a shift to continuous perfusion will likely be gradual.

Introduction to Fluidization

November
2014
Back To Basics
Raymond Cocco, S. B. Reddy Karri, Ted Knowlton
Fluidized beds offer excellent heat transfer, and have the unique ability to move a wide range of solid particles in a fluid-like fashion. This article explains the basics of fluidization theory and outlines how to design a typical fluidized bed.

Use Spreadsheets for ChE Problem-Solving

August
2016
Back To Basics
David E. Clough
This article will help you improve your Excel spreadsheet skills and will provide you with tools to solve common chemical engineering problems.

Understand the Basics of Membrane Filtration

April
2013
Back To Basics
Hua Wang, Hongyi Zhou
Membrane filtration is an integral part of many industrial processes, as it is often more environmentally sustainable and cost-effective than other separation technologies

Particle Technology

eLearning (online) Course
Difficulties in handling or processing powders are often overlooked and can result in production stoppages. Gain a practical introduction to particle...

Process Control for Microreactors

August
2001
Instrumentation
Don  Humbert, Lech  Znamirowski, Olgierd A. Palusinski, Sarma Vrudhula
Field-programmable analog arrays coupled with microreactor technology promise to change the way plants are built, as well as the methods by which their processes are designed and controlled.

Understand Pilot-Plant Design Specifications

May
2016
Plant Design
Adam Whalley, P.Eng.,
Although pilot- and commercial-scale plants may appear similar, they must be designed with different objectives in mind. Find out how the design criteria for pilot and commercial plants differ, and why commercial specifications should not be applied to pilot plants.

Put More Punch Into Catalytic Reactors

March
2003
Reactions and Separations
Ed Fontes, Olof Hernell, Phil Byrne
Using equation-based modeling to design these reactors can optimize their efficiency and throughput.

Reduce Piloting Time and Cost

July
2011
Process Development
David A. Berg, Michael T. Cleary
Pilot-scale experimentation is essential to establish a sound foundation for a new chemical processing unit. These best practices can reduce the time and cost involved in process development.

Basics of the Chemical Industry

eLearning (online) Course
The chemical industry value chain is complex. In this online course, you’ll gain a high-level review of the manufacture and markets for roughly 70...

Engineering Organs: Heart and Esophagus

December
2007
SBE Special Section
Buddy D. Ratner
The potential for tissue engineering to transform the practice of medicine is enormous. Chemical engineers will play important roles in this revolution.

Accurately Predict the VLE of Thiol-Hydrocarbon Mixtures

September
2004
Reactions and Separations
Wayne Sim, Vince Tassone, Chorng H. Twu
This methodology can be used to calculate vapor-liquid equilibria (VLE) between thiols and hydrocarbons at any composition, temperature or pressure to improve gasoline fractionation processes.
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