Chemical Engineering Practice

Application of Quality by Design in API Process Development

Conference Presentation
AIChE Annual Meeting
Wednesday, October 31, 2012 - 2:45pm-3:00pm
Design of Experiments (DOE) is the most effective method to achieve product and pro­cess efficiency and optimization. Design of Experiment (DOE)...

A QbD Approach to the Process Development of Tofacitinib

Conference Presentation
AIChE Annual Meeting
Wednesday, October 31, 2012 - 1:15pm-1:30pm
Tofacitinib citrate (CP-690,550-10) is currently being evaluated for the treatment of rheumatoid arthritis, psoriasis and other diseases. An NDA has...

Dry Reforming of Methane Using Rh Substituted Pyrochlores

Conference Presentation
AIChE Annual Meeting
Wednesday, October 31, 2012 - 1:15pm-1:30pm
Dry (CO 2 ) reforming of methane (DRM) to syngas (H 2 and CO) has been well-studied over a number of catalysts. The high temperatures needed to...

Fuel Processing: Renaissance of the Second Decade (Keynote)

Conference Presentation
AIChE Annual Meeting
Tuesday, October 30, 2012 - 3:15pm-3:45pm
The early development of fuel processing technologies for fuel cell systems was, to a great extent, driven by fuel cell automobile programs. At the...

Engineering Pellets of Biomass Blends

Conference Presentation
AIChE Annual Meeting
Tuesday, October 30, 2012 - 3:15pm-3:45pm
Transportation and handling of lignocellulosic biomass are often challenging and expensive due to low bulk density, in the range of 60-80 kg/m 3 for...

Insights From Glucose Pyrolysis for Cellulose Pyrolysis

Conference Presentation
AIChE Annual Meeting
Tuesday, October 30, 2012 - 1:30pm-1:45pm
Experimental and predicted kinetics of glucose, the monomer of cellulose, provides quantitative and qualitative insights into the pyrolysis of...

Optimal Design of Transient Microreactor Experiments

Conference Presentation
AIChE Annual Meeting
Tuesday, October 30, 2012 - 12:30pm-1:00pm
Development of synthetic routes for active pharmaceutical ingredient (API) synthesis is increasingly performed using microreactors, because their use...

A Novel QbD Tool for Statistical Data Analysis

Conference Presentation
AIChE Annual Meeting
Tuesday, October 30, 2012 - 10:15am-10:30am
One of cornerstones of Quality by Design (QbD) is Design of Experiments (DoE). However, in addition to DoE, ICH Q8 (R2) recommends an enhanced...

Modelling of a Filter Drying Process

Conference Presentation
AIChE Annual Meeting
Monday, October 29, 2012 - 5:15pm-5:45pm
Filter drying, also referred to as vacuum contact drying, is a process widely used in the pharmaceutical industry to remove water or organic solvents...

Scale-up of SAPO-34 Membranes for CO2/CH4 Separation

Conference Presentation
AIChE Annual Meeting
Monday, October 29, 2012 - 9:30am-10:00am
SAPO-34 membranes have pores with a diameter of approximately 0.38 nm and have the potential to be used for large scale removal of CO 2 impurities...

The Mixed Matrix Membrane Story

Conference Presentation
AIChE Annual Meeting
Monday, October 29, 2012 - 9:00am-9:30am
The talk will highlight the evolution of Mixed Matrix Membranes (MMM), developed in the mid-1980s. The talk will first provide an introduction into...

Modeling of LNG Spills Into Trenches and Troughs

Conference Presentation
AIChE Spring Meeting and Global Congress on Process Safety
Thursday, April 5, 2012 - 12:00am
Trenches and troughs are commonly used in LNG storage and transfer facilities to contain potential LNG spills. The trenches are concrete-lined...

Furnace Stories

Conference Presentation
AIChE Spring Meeting and Global Congress on Process Safety
Thursday, April 5, 2012 - 12:00am
The cracking furnace is the heart of the ethylene plant, consuming the most energy, adding the most value and with the potential to cause the most...

Capital Cost Targeting of Total Site Heat Recovery

Conference Presentation
AIChE Spring Meeting and Global Congress on Process Safety
Wednesday, April 4, 2012 - 12:00am
Heat recovery on Total Site level can provide a considerably high potential for energy saving. It offers additional degrees of freedom for heat...

Hydrocarbons Turnarounds EHS Readiness

Conference Presentation
AIChE Spring Meeting and Global Congress on Process Safety
Wednesday, April 4, 2012 - 12:00am
The Dow Hydrocarbons Business has a thorough process for managing excellent EHS performance during Turnarounds. We name an EHS Focal Point for each...

Panel Discussion on Turnaround Excellence

Conference Presentation
AIChE Spring Meeting and Global Congress on Process Safety
Wednesday, April 4, 2012 - 12:00am
A panel of industry experts will discuss topics of interest to Ethylene Producers with respect to turnaround excellence. Topics will be solicited...

Hydrotreating of Biooils to Jet Fuels: An Overview

Conference Presentation
AIChE Spring Meeting and Global Congress on Process Safety
Wednesday, April 4, 2012 - 12:00am
This paper will give an overview of the current status of jet fuels production from hydrotreating of biooils, including vegetable oils and microalgae...

Hydroprocessing Design - Tutorial

Conference Presentation
AIChE Spring Meeting and Global Congress on Process Safety
Wednesday, April 4, 2012 - 12:00am
Hydroprocessing or hydrotreating is the key technology to clean, to refine, and to convert crude oils into valuable products, such as gasoline and...

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