Chemical Engineering Practice

Streamlining Crystallization Process Design

January
2004
Fluids and Solids Handling
Christianto  Wibowo, Lionel O'Young, Ka M. Ng
Use phase diagrams to develop reliable crystallization processes quickly and cost effectively.

Process Safety Beacon: Understand Chemical Compatibility

July
2016
Process Safety Beacon
Chemical compatibility charts can be used to determine the chemical reactivity of thousands of common hazardous chemicals, the compatibility of absorbents, and the suitability of materials of construction in chemical processes.

Piloting Bioreactors for Agitation Scale-Up

February
2008
Reactions and Separations
Gregory T. Benz
This article offers guidance on how to design appropriate experiments to measure scalable data for agitation in both aerobic and anaerobic bioreactors.

Nanosensors: Evolution, Not Revolution...Yet

June
2008
News Feature
Suzanne A. Shelley
Promising nanotechnology-enabled sensors, monitoring devices and analytical instruments continue to advance toward commercialization for diverse industrial, environmental, medical and military applications— but hurdles remain.

Choose the Right Gas Sensor

September
2009
Instrumentation
Sandra Barnes
Selecting a sensor for continuous monitoring involves many considerations. This article discusses the types of sensors available, their applicability and limitations, and how to choose an appropriate sensor to protect people and equipment.

CEP: Process Automation Corner - Process Simulation and Process Control

September
2013
Process Automation Corner
Terry McMahon
Chemical engineers have been practicing process simulation since the advent of the profession in the early 20th century. It was called process design and inevitably involved simplifying assumptions, including that steady-state process conditions had...

Determining Discharge Rates of Particulate Solids

May
2016
Fluids and Solids Handling
Shrikant Dhodapkar, Karl V. Jacob, Madhusudhan Kodam
Many factors affect the flowrate of bulk solids. This article reviews the underlying physics of solids flow and explains how to calculate the discharge rate of solids from processing and handling equipment.

Modeling Reactive Absorption

January
2009
Reactions and Separations
Eugeny Kenig, Panos Seferlis
Effective modeling of reactive absorption enhances system design, improves experiment planning for parameter-estimation, and facilitates process operation and control decisions.

SBE Special Section: Biopharmaceuticals - Continuous Processing in Upstream Operations

December
2015
SBE Special Section
Chun Chen, Chetan T. Goudar, Huong Le
Perfusion technology offers many benefits over fed-batch processing, such as reducing the size of the bioreactor, which reduces capital costs and enables the use of single-use bioreactor technology. Despite these advantages, a shift to continuous perfusion will likely be gradual.

Introduction to Fluidization

November
2014
Back To Basics
Raymond Cocco, S. B. Reddy Karri, Ted Knowlton
Fluidized beds offer excellent heat transfer, and have the unique ability to move a wide range of solid particles in a fluid-like fashion. This article explains the basics of fluidization theory and outlines how to design a typical fluidized bed.

Understand the Basics of Membrane Filtration

April
2013
Back To Basics
Hua Wang, Hongyi Zhou
Membrane filtration is an integral part of many industrial processes, as it is often more environmentally sustainable and cost-effective than other separation technologies

Process Control for Microreactors

August
2001
Instrumentation
Don  Humbert, Lech  Znamirowski, Olgierd A. Palusinski, Sarma Vrudhula
Field-programmable analog arrays coupled with microreactor technology promise to change the way plants are built, as well as the methods by which their processes are designed and controlled.

Understand Pilot-Plant Design Specifications

May
2016
Plant Design
Adam Whalley, P.Eng.,
Although pilot- and commercial-scale plants may appear similar, they must be designed with different objectives in mind. Find out how the design criteria for pilot and commercial plants differ, and why commercial specifications should not be applied to pilot plants.

Put More Punch Into Catalytic Reactors

March
2003
Reactions and Separations
Ed Fontes, Olof Hernell, Phil Byrne
Using equation-based modeling to design these reactors can optimize their efficiency and throughput.

Reduce Piloting Time and Cost

July
2011
Process Development
David A. Berg, Michael T. Cleary
Pilot-scale experimentation is essential to establish a sound foundation for a new chemical processing unit. These best practices can reduce the time and cost involved in process development.

Accurately Predict the VLE of Thiol-Hydrocarbon Mixtures

September
2004
Reactions and Separations
Wayne Sim, Vince Tassone, Chorng H. Twu
This methodology can be used to calculate vapor-liquid equilibria (VLE) between thiols and hydrocarbons at any composition, temperature or pressure to improve gasoline fractionation processes.

Stem Cell Engineering 101

November
2010
SBE Special Section
Jonathan Monk
Stem cells are poised to transform medical treatments for a host of diseases and malignant conditions. Translating stem cell research into clinical therapies, disease models, and drug-screening platforms will require a combination of sound science...

Engineering Organs: Heart and Esophagus

December
2007
SBE Special Section
Buddy D. Ratner
The potential for tissue engineering to transform the practice of medicine is enormous. Chemical engineers will play important roles in this revolution.

Selecting Laboratory Reactors

August
2007
Reactions and Separations
Francesco Picciotti, Marcello Picciotti
This article outlines some of the considerations involved in selecting and specifying a reactor system for research and development applications.

Nanomaterials: What are the Environmental and Health Impacts?

December
2008
Critical Issues
Nastassja Lewinski
As with previous emerging technologies, there have been uncertainties and concerns about the environmental and health risks associated with nanotechnology. This article reviews some of the ongoing efforts to better understand and characterize...

Understanding Crystallization and Crystallizers

October
2006
Fluids and Solids Handling
Lionel O'Young, Ketan D. Samant
Gain qualitative insight into the basic mechanisms of crystallization, the principles of crystallizer operation, and the ways in which these concepts relate to the selection and application of the various crystallizer configurations in industrial...

Bridge the Gap with Semicontinuous Distillation

August
2001
Reactions and Separations
James R. Phimister ,  Warren D. Seider
This processing strategy combines the advantages of batch and continuous operation, providing flexibility and efficiency in a single design.

Evaluating the Economics of Desalination

December
2002
Heat Transfer
Hisham M. Ettouney, Hisham T. El-Dessouky, Peter J. Gowin, Ron S. Faibish
This article presents an in-depth analysis of thermal and membrane desalination economics and outlines a simple procedure for calculating the unit product cost for various desalination processes.

Nano-technology: Fueling the Chemical Industry's Future

November
2003
Special Section
Daniela L. Carrillo, Tim Harper, Paul Holister, Mindy Rittner, Mihail C. Roco, Cristina Roman Vas
Nanotechnology, as a whole, is still an emerging area with the need to make progress in both scientific and technological terms before enormous commercialization of products may occur. Nevertheless, commercial products are out there — more in some...

CEP: Chem Economics - Manufacturing Renaissance Takes Hold in the U.S.

October
2012
Chem Economics
T. Kevin Swift
Many living in the Rust Belt — the northeastern region of the U.S. that experienced significant de-industrialization during the 1970s through the 2000s — got an up-close look at the decline in manufacturing in the U.S. In the wake of the Great...

Using Chromatography to Separate Complex Mixtures

December
2010
Back To Basics
Nathalie Fraud
Purifying high-value mixtures, such as pharmaceuticals, can be an expensive undertaking. Choosing the correct chromatography methods can improve purity and reduce processing time and cost.

Nanotechnology: A Guide to Nano-Objects

May
2011
On The Horizon
Sravani Gullapalli, Michael Wong
Rapid change in the field of nanotechnology can make it hard to keep track of the latest nanomaterial developments. Here's a primer on the most common shapes, sizes, and compositions of nano-objects.

Optimizing Crystallizer Scaleup

June
2003
Fluids and Solids Handling
Wayne Genck
Explore how mixing parameters impact the crystallization process and recommend ways to improve the likelihood of successful scaleup. The concepts of nucleation and growth, types of mixing, design considerations, agitator parameters and scaleup...

Ionic Liquids for Aromatic Extraction: Are They Ready?

December
2006
Reactions and Separations
Sachin T. Anjan
Ionic liquids have already moved into the commercial arena as reaction solvents. This article compares them to conventional solvents and examines their potential for the extraction of benzene, toluene and xylene from reformate.

Predictive Modeling in Catalysis - From Dream to Reality

June
2009
On The Horizon
Ana G. Maldonado
In silicocatalyst optimization is the ultimate application of computers in catalysis. This article provides an overview of the basic concepts of predictive modeling and describes how this technique can be used in catalyst and reaction design.

Supplemental Nanobiotechnology Tables

February
2006
SBE Special Section
These tables offer a snapshot of the many companies, research organizations and universities working in nanotechnology, nanoscience, nanobiotechnology and other variations of the term that has been coined to describe a revolutionary approach to...

Applying Mass and Energy Balances to Spray Drying

December
2009
Back To Basics
Tim Langrish
Mass and energy balances are not just for process and equipment design. They can also be used to improve dryer operations by answering various “what-if” questions about temperatures, flowrates, and moisture contents. <br><br>

Increase Powder Flow via Gas Injection

July
2006
Fluids and Solids Handling
John W. Carson, Herman Purutyan, Thomas G. Troxel
Fluidization and air-assisted discharge are two ways to optimize fine-solids handling. However, the choice of technology is as important as designing and operating the system properly.

Understand Discrete Nanoscale Transport

June
2008
On The Horizon
Anh-Tuan Dinh, Samir Mitragotri, Chinmay Pangarkar
Unlike mass, energy and momentum transfer, which are described by continuum equations, the movements and interactions of the nanoscale entitites within a cell constitute the transport phenomenon known as discrete nanoscale transport (DNT).

Nanotechnology: Cause for Concern?

September
2007
News Feature
Kristine Chin
Nanotechnology— it's a small science with big stakes. Some of the unique properties that make nanoscale materials useful may also pose hazards to humans and the environment. Can the EPA find a way to effectively regulate these tiny high-tech...

Designing Multistage Agitated Reactors

January
2014
Reactions and Separations
Gregory Benz
This article bridges the gap between theory and practice for the design of continuous-flow mechanically agitated reactors, with a focus on mechanical and hydraulic issues.

Design Principles for Liquid-Liquid Extraction

November
2015
Reactions and Separations
Joerg Koch, Glenn Shiveler
Many factors must be evaluated when developing a liquid-liquid extraction process. Here are some of the important parameters to consider as you go from laboratory testing to commercial-scale operation.

CEP: Chem Economics - Plastic Additives are Poised for Growth

July
2012
Chem Economics
T. Kevin Swift
Not all polymers are useful and/or processable in their natural form. Thus, functional chemicals are added to polymer resins to facilitate processing and to enhance, extend, or otherwise modify the properties of the plastic products manufactured from polymer resins. Such plastic additives represent a $4.6-billion business in the U.S.

Bioseparation Basics

October
2014
Back To Basics
Roger G. Harrison
Bioseparations are critical to the field of biochemical engineering. Each bioseparation process must be tailored to separate, purify, or recover the desired bioproduct. This article gives an introductory overview of filtration and chromatography — two key bioseparation unit operations.

Fulfilling the Promise of Nanomedicine

February
2006
SBE Special Section
Rita D'Aquino with Tim Harper, Cristina Roman Vas
Leveraging nanotechnology in the life science industries has given scientists new tools with which they have the potential to transform the world of medicine.

Developing Crystallization Processes

March
2011
Reactions and Separations
Christianto Wibowo
With solid-liquid equilibrium as its foundation, this systematic approach makes it easy to identify operating regions and theoretical yield to maximize the desired product.

Selecting Sensors for Safety Instrumented Systems

July
2015
Back To Basics
Jessica Lo, Erik Mathiason, Chad McGuire
A plant’s safety instrumented system (SIS) is critical in preventing process safety incidents. Use this guide to help choose the proper sensors for your plant’s SIS.

Producing Nitrogen via Pressure Swing Adsorption

June
2012
Reactions and Separations
Svetlana Ivanova, Robert Lewis
Pressure swing adsorption (PSA) can be a cost-effective method of onsite nitrogen generation for a wide range of purity and flow requirements.

Best Practices for Pilot-Plant Piping

April
2014
Fluids and Solids Handling
Richard Palluzi
Pilot-plant piping is subject to more-frequent modification than typical process plant piping, and must be able to accommodate a range of media, temperatures, and pressures during its lifetime. Use this guide to determine which piping, tubing, and fittings are optimal for your pilot plant application.

Predict Incidents with Process Safety Performance Indicators

February
2016
Safety
Wahid Azizi
Become a seer of process safety incidents with carefully chosen process safety performance indicators (PSPIs). A PSPI program developed using the barrier-based or tier-based approach will serve as your crystal ball.

Understand Flow Patterns in Glass-Lined Reactors

November
2004
Reactions and Separations
Kevin J. Bittorf, David S. Dickey, Keith E. Johnson , Christopher J. Ramsey
Physical modeling and computer simulation provide insights into the performance of a glass-lined reactor.

Safely Handle Powdered Solids

December
2005
Fluids and Solids Handling
Stanley S. Grossel, Russell Kahn, Daniel E. Silva, Robert Zalosh
Understand some of the accident scenarios that result in dust explosions, and follow these suggestions for preventing them.

Environmental Law for Chemical Engineers

February
2012
Back To Basics
Mary Ellen Ternes
A basic understanding of environmental law is beneficial for all chemical engineers. Learn how laws are proposed, made, and implemented, and ways to avoid incurring unnecessary penalties.

Calculate Financial Indicators to Guide Investments

September
2013
Back To Basics
John Anderson, Andy Fennell
Engineers can become better informed about their work with an increased familiarity of basic financial indicators. Use these insights to help ensure that the projects you work on are those that are most likely to become financial successes.

Modeling Chemical Reactors

February
2015
Reactions and Separations
Ed Fontes
Models can be used to describe chemical reactors to help solve problems and optimize processes, while saving time, money, and resources.

Determining Manufacturing Costs

January
2009
Back To Basics
John Anderson
Making early estimates of a product's cost components enables developers to manage resources wisely and evaluate the product's economic viability.

Pages

Subscribe to Chemical Engineering Practice