Process Design & Development

Use these guidelines to avoid potential caking problems. The key steps are to select a material characterization method, identify the factors that can be feasibly controlled and conduct tests to confirm that process/handling changes yield the...

Fluidization and air-assisted discharge are two ways to optimize fine-solids handling. However, the choice of technology is as important as designing and operating the system properly.

As businesses strive to improve productivity, process modeling can be a powerful tool. This article explores the role of modeling in enhancing the effectiveness and efficiency of process development and manufacturing.

To assure reliable and safe operation of a dust collector, apply the basic principles of chute and hopper design — which are based on the dust's fundamental flow properties.

With short residence times and various design options, these dryers are an efficient and economical choice for a wide variety of solids.

Following this procedure to identify a basic exchanger geometry without performing a full exchanger design and to evaluate where and when heat transfer enhancement can be of benefit.

Designing an economically competitive and environmentally sustainable fermentation route means considering the downstream separations needed to capture the final product during the initial process design.

To function properly at optimum capacity and efficiency, multi-pass trays must be designed so that the liquid and vapor flows are properly balanced. This article provides guidance on how to achieve that.

Issues such as sterility, isolation and contamination must be considered when choosing seals for use in biotech and pharmaceutical processes. This overview describes common types of seals and offers guidance on selecting the appropriate seal for...

Specialty metals should be considered for processes that push beyond the corrosion limits of steel. New composites and surface alloy technologies expand the options for defending against corrosion.