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Mixing

Inline Mixing Device for Medical Applications

Nov 10, 2009
Yves Delmotte
In the surgical field, the mixing of two combined fluid streams is required to form fibrin glue, used as a tissue sealant or a hemostat. The sealant components, fibrinogen and thrombin, have different viscosities, respectively 150 and 1 cps at 37°C. The viscosity of fibrinogen depends on the...

Mixing Scale-Down Studies for the Scale-Up of Beer Fermentation

Nov 10, 2009
Alvin Nienow
Beer fermentations have traditionally been undertaken without the use of mechanical agitation with mixing being provided only by the CO2 evolved during the batch process. This approach has largely been maintained because of the belief in industry that rotating agitators would damage the yeast. In...

Aerobic Fermenter Scale-up: Why Equal Mass Transfer Scale-up Doesn't Always Work

Nov 9, 2009
Julian B. Fasano
Transferring oxygen to the liquid is only one of several steps that must occur in an aerobic fermentation. After the oxygen is transferred to the liquid, the liquid must be thoroughly mixed throughout the vessel. Then the oxygen must diffuse through the cell wall before finally being metabolized...

Understand the Real World of Mixing

March
2010
Back To Basics
Thomas Post
Most chemical engineering curricula do not adequately address mixing as it is commonly practiced in the chemical process industries. This article attempts to fill in the gaps by explaining flow patterns, mixing techniques, and the turbulent,...

How to Scale-Up Mixing Processes in Non-Newtonian Fluids

May
2003
Fluids and Solids Handling
Christopher Henry , Robert J. Wilkens,  Lew E. Gates
This article will describe the relationships that must be understood to scale-up fluid mixing processes in non-Newtonian, power-law fluids. The principles described apply to both close-clearance impellers, such as anchors and helixes, and to open...

Understand Temperature Change in Process Stream Mixing

September
2006
Heat Transfer
Anil K. Mehrotra, Dharmendra Tiwary
The isobaric and adiabatic mixing of process streams can yield an outlet stream temperature that is either in between, higher than, or lower than the inlet stream temperatures. This article uses simulation to explore temperature-change scenarios in...

Find Mixing Success through Failures - Part 1

October
2008
Fluids and Solids Handling
David S. Dickey, Gary K. Patterson
Understanding when and why mixing fails in the laboratory is often the only way of avoiding a similar failure in a production-scale reactor.

Find Mixing Success Through Failures - Part 2

December
2008
Fluids and Solids Handling
David S. Dickey, Gary K. Patterson
Understanding when and why mixing fails in the laboratory is often the only way of avoiding a similar failure in a production-scale reactor. Here we examine mixing in stirred-tank reactors and provide guidance on scale-up.

Optimize Mixing by Selecting the Proper Baffles

February
2002
Fluids and Solids Handling
Julian B. Fasano, Kevin J. Myers, Mark F. Reeder
It is common knowledge that baffles promote better flow in an agitated vessel, but how to apply them and what kind to use take some ingenuity.

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