Biological Engineering

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Society for Biological Engineering (SBE)

SBE is a global technological community that promotes the integration of engineering with biology and realize its benefits through bioprocessing, biomedical, and biomolecular applications. SBE provides opportunities for interaction of engineers and scientists, develops products and services bring value to the broad biological engineering community, and infuses awareness of biological engineering among all functions and activities of AIChE.

Forest Bioproducts Division (FBP)

The Forest Bioproducts Division promotes knowledge sharing and networking on topics dealing with products obtained from forest resources and other lignocellulosic materials.

Pharma Turns to Gut for New Drugs

January 25, 2016
The past few years have been full of stories about how a number of serious conditions could be treated or cured by introducing certain bacteria to the digestive system. Now, a...

Bioreactor Design for Chemical Engineers

August
2011
Back To Basics
Gregory T. Benz
Fermentation processes are based on chemical engineering principles. Understand these concepts to achieve optimal bioreactor design.

Genomatica: 15 Year Journey (and counting)

Conference Presentation
Metabolic Engineering Conference
Sunday, June 15, 2014 - 10:00am-11:00am
As a founder and CEO, Christophe Schilling has led Genomatica from a developer of metabolic engineering tools to a position of leadership in biotech...

Green Chemistry and Engineering: A Pathway to Sustainability

November, 2013
Green Chemistry and Engineering presents the green approach as an essential tool for tacking problems in chemistry. This text covers introductory concepts in general, organic, inorganic, and analytical chemistry as well as biochemistry.

SBE Update: The Merging of Bio and Nano

December
2012
SBE Special Section
June Wispelwey
Earlier this year, the Society for Biological Engineering (SBE) organized its Sixth International Conference on Bioengineering and Nanotechnology (ICBN), which focused on bio-nanoscience and bioengineering for translational medicine. The conference...

Bioactive Devices: Uniting Form with Function

March
2013
SBE Special Section
Sujata Bhatia
Bioactive implants that combine a medical device with one or more biologic therapeutic agents show promise for the targeted treatment of complex medical conditions. Implantable medical devices, such as stents, grafts, and joint replacements, are...

Bio-Based Materials in the New Bio Economy

May
2012
SBE Special Section
Manjusri Misra, Amar Mohanty, Murali M. Reddy
Biological feedstocks are expected to gradually replace some fossil-based raw materials to create eco-friendly products, from car parts and packaging materials to electronic devices and other consumer goods - laying the foundation for a reduced-carbon economy.

Producing Fuels and Chemicals from Lignocellulosic Biomass

August
2008
SBE Special Section
Mark Holtzapple, Rocio Sierra, Aaron Smith, Cesar Granda and Mark T. Holtzapple
As oil and natural gas prices rise, lignocellulosic biomass becomes a viable feedstock for the fuel and chemical industries— provided key issues are addressed.

A MagDot-Nanoconveyor Assay Detects and Isolates Molecular Biomarkers

December
2012
SBE Special Section
Jeffrey Chalmers, Maryam B. Lustberg, M.D., Kalpesh Mahajan, Brandon Miller, Gang Ruan, Ratnasingham Sooryakumar, Gregory B. Vieira, Jessica Winter
The ability to quickly analyze, separate, and manipulate multiple types of biomarkers from small sample volumes is a significant step toward personalized medicine.

SBE Special Section: Biopharmaceuticals - SBE Update: Continuous Progress in Biopharmaceuticals

December
2015
SBE Special Section
Darlene Schuster
The goal of bioprocessing is to optimize natural or artificial biological systems by manipulating prokaryotic and eukaryotic cells and their environment to produce biopharmaceutical products. A bioprocess is divided into upstream and downstream operations. Upstream processing encompasses the steps from preliminary unmodified cell line culture to the mature modified cell culture and harvest; downstream processing includes the separation and purification of the biologics from the mature activated cell culture. These operations have typically been performed as batch processes.

SBE Update: Drug Delivery and Chemical/Biological Engineering

March
2013
SBE Special Section
June Wispelwey
Although you might not associate drug delivery with chemical engineering, the principles of chemical engineering — such as mass and energy balances, transport phenomena, reaction kinetics, and particle technology — are intimately involved in drug...

SBE Supplement: Biochemical Engineering - Cell-Free Bioprocessing

November
2013
SBE Special Section
James Swartz
The ability to exploit a cell’s contents and capabilities unimpeded by cell walls opens new opportunities for the field of biochemical engineering. Cell-free biology could become the basis for making products from hydrogen to cancer vaccines and more.

Engineered Protein Templates Synthesize Inorganic Nanomaterials

December
2012
SBE Special Section
Arunagirinathan Adhimoolam, Sarah Heilshorn, Kelly N. L. Huggins, Alia Schoen, David T. Schoen
This powerful biomimetic method is a fast, flexible way to produce a wide range of inorganic nanostructures from a single protein scaffold.

Biology as a Basis for Biochemical Engineering

July
2013
Back To Basics
Sujata Bhatia
Biochemical engineering demonstrates the versatility of the living cell as a miniature reactor. Living cells can be genetically engineered to produce specific proteins, tuned to manufacture novel enzymes, and optimized to guarantee genetic stability and consistent production of desired products.

SBE Special Section: Biopharmaceuticals - Continuous Processing in Downstream Operations

December
2015
SBE Special Section
Todd Przybycien, Professor Nigel Titchener-Hooker
The transition from batch to continuous downstream processing of biologics has been gradual, with some processes integrating continuous and batch operations. A fully continuous, commercial-scale downstream process has yet to be implemented. Find out why, as well as the current status of the technology.

Using Genomic Tools to Improve the Production of Biologics

November
2009
SBE Special Section
Dr. Wei-Shou Hu, Nitya M. Jacob, Wei-Shou Hu, Bernard Liat Wen Loo, and Miranda Yap
Recombinant DNA technology transforms mammalian cells into factories for protein-based therapeutics. New techniques provide chemical engineers with a better understanding of the process as well as the cells themselves.

Algal Biofuels: The Research

March
2011
SBE Special Section
Kuan-Chen Cheng, Kimberly Ogden
The individual technical elements of the algae-to-biofuels process have already been demonstrated at the laboratory scale. Ongoing research seeks to refine the technology to enable scaleup to commercial production.

Recombinant Protein Therapeutics from CHO Cells -- 20 Years and Counting

October
2007
SBE Special Section
Dr. Wei-Shou Hu, Karthik P. Jayapal, Katie F Wlaschin, Wei-Shou Hu and Miranda G. S. Yap
The CHO cell is at its height of technological prominence thanks to its adaptability to various culture conditions and plasticity in the context of genetic alterations. With further research, the application ofCell Culture Strategies based on...

SBE Special Section: Biopharmaceuticals (Full 19-Page Supplement)

December
2015
SBE Special Section
Chun Chen, Chetan T. Goudar, Huong Le, Todd Przybycien, Nigel Titchener-Hooker
SBE Update: Continuous Progress in Biopharmaceuticals; Continuous Processing in Upstream Operations; Continuous Processing in Downstream Operations; A Look at the Regulations

Synthetic Biology: Putting Together the Pieces

July
2015
On The Horizon
Michelle Bryner
Synthetic biology represents a new way of building biological systems via engineering tools and principles. Genetic components and pathways will be created to reprogram organisms, endowing them with novel functions for a wide range of applications.

New Products: December 2015

December
2015
New Products
Instrumentation Temperature Transmitters Feature Dual Sensor Inputs The THZ 3 and TDZ 3 two-wire (loop-powered) temperature transmitters provide an isolated and linear 4–20-mA output proportional to input. They can be configured quickly and easily...

The Blood-Brain Barrier and Drug Delivery

March
2013
SBE Special Section
William Olbricht
To maintain favorable conditions in the brain, the blood-brain barrier limits mass transfer across brain tissue. However, it also restricts the systemic delivery of compounds to treat neurological disorders. Several treatment alternatives to bypass...

New Bandage Glows in Presence of Infection

December 22, 2015
British researchers have created a bandage that warns of common infections by turning a fluorescent green within four hours of pathogen detection. While a bandage often helps to...

SBE Special Section: Lignocellulosic Biofuels - Full 32-Page Supplement

March
2015
SBE Special Section
Tristan R. Brown, Robert Brown, Sergio C. Capareda, Bruce E. Dale, David Edwards, Vonnie Estes, Cesar Granda, Mark Holtzapple, Sagar Lonkar, Darlene Schuster, Charles Wyman
SBE Update; The Need for Biofuels; Producing Biofuels via the Thermochemical Platform; Producing Biofuels via the Sugar Platform; Producing Biofuels via the Carboxylate Platform; Scaling Up Bioenergy Technologies; Commercial-Scale Production of Lignocellulosic Biofuels

Photo Highlights from 2015 Honors Ceremony

November 9, 2015
The 2015 Institute and Board of Directors’ Award winners were given at the Honors Ceremony at the Annual Meeting in Salt Lake City. These are among AIChE’s most prestigious awards...

CEP: News Update

August
2015
News Update
Sponge-Like Catalyst Makes Bioplastic Cheaper and Greener; LED Combines Optoelectronic Powerhouses; New Water Splitter Produces Hydrogen; Algal Fuel Gets a Boost; and more.

Polymer Nanotubes that Resemble Nerve Structures

August 26, 2015
Researchers at Sandia National Laboratories have created linkages of polymer nanotubes that resemble the structure of a nerve and are capable of transmitting electrical impulses...

More ChE Manufacturing: Rebuilding the Body

October 3, 2012
Tissue engineering is potentially a new area of custom ChE-style manufacturing, illustrating how our approaches to manufacturing go beyond the popular view that manufacturing is...

July 2015 CEP Preview

July 6, 2015
In this issue, get tips for selecting sensors for your plant's safety instrumented system (SIS), a guide to mixing, some of the latest development in biological engineering, and...

Re-engineering Mosquitos to Fight Disease

January 16, 2013
Every year, there are over 50 million cases of dengue fever carried by mosquitos. Find out how one biotech company is seeking a solution to control the world's mosquito population...

Nanoparticle versus Cancer

February 22, 2011
Whenever cancer is discussed, a familiar phrase is often heard: the earlier it's caught, the better the chances of survival. Early detection is the next best thing to avoiding...

Bio-Energy Boom Creating ChE Jobs in New Mexico

January 30, 2012
Located in the heart of the revitalized oil-rich Permian Basin , just five miles from west Texas, dusty and dry Hobbs, New Mexico, has always been considered the "Oil Capitol of...

Celebrating The Science and Art of Beer

June 10, 2013
To craft the astounding variety of modern beers, today's chemical engineers integrate the age-old and practical with science and whole-system thinking.

Robots Help Assemble Anti-Microbial Compounds

June 3, 2015
Just last week we wrote about antibiotic resistance and new rapid testing , and this week comes more promising news about the development of new antimicrobial compounds. A story...

November 2010 CEP Preview

November 13, 2010
Stem cells are poised to transform medical treatments for a host of diseases and malignant conditions. Translating stem cell research into clinical therapies, disease models, and...
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