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Biological Engineering

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Society for Biological Engineering (SBE)

SBE is a global technological community that promotes the integration of engineering with biology and realize its benefits through bioprocessing, biomedical, and biomolecular applications. SBE provides opportunities for interaction of engineers and scientists, develops products and services bring value to the broad biological engineering community, and infuses awareness of biological engineering among all functions and activities of AIChE.

Forest Bioproducts Division (FBP)

The Forest Bioproducts Division promotes knowledge sharing and networking on topics dealing with products obtained from forest resources and other lignocellulosic materials.

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QbD In Dry Powder Inhaler Development

Oct 19, 2011
David Morton
Summary Developing products comprising un-bound fine cohesive powders throws up significant challenges. Dry powder inhalers present a prime example. Why? Because the behaviour of fine cohesive particle behaviour is notoriously complex, and notably more so than any single phase solid, liquid or...

Use of Single-Use Technologies In Downstream Purification of Mabs - A Case Study

Oct 19, 2011
Venkatesh Natarajan
The employment of single-use technologies in the downstream processing of biologics in general and monoclonal antibodies in particular is gaining significant traction in the industry. Their use eliminates cleaning validation requirements and can potentially offer significant savings in capital...

CMC Reviewer Expectations for ANDAs Using QbD Approaches

Oct 18, 2011
Robert L. Iser
There has been an increase in science and risk-based approaches under the Quality by Design paradigm in new drug submissions to the FDA. There are particular challenges for generic drug manufacturers with respect to using QbD approaches, especially with more complex dosage forms, such as modified...

The Role of Acidic Catalyst Support On the Catalytic Upgrading of Bio-Oils

Oct 18, 2011
Sunya Boonyasuwat
Catalytic conversion of bio-oil vapor has attracted considerable interest as a promising pathway for upgrading. In this work, the reaction of anisole and guaiacol, phenolic model compounds commonly existing in bio-oils, were studied over an acidic silica-alumina catalyst and at varying space times...

Cellulose Extraction From Rice Hulls Using Ionic Liquids

Oct 18, 2011
Charles J. Coronella
Over one fifth of calories consumed by humanity are from rice. Consequently, vast quantities of rice hulls are disposed of as waste, since the hull constitutes 20% of rice mass. Standard practice for disposal of rice hulls is burning, generating pollution and CO 2 , or thrown away in vast...

Cellobiose Hydrolysis Using Acid-Functionalized Nanoparticles

Oct 18, 2011
Leidy Peña
Mineral acids have been used effectively for the pretreatment of cellulosic biomass to improve sugar recovery and promote its conversion to ethanol; however, substantial capital investment is required to enable separation of the acid, and corrosion-resistant materials are necessary. Disposal and...

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