Biological Engineering

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From Biochemical Engineering to Synthetic Biology: A Short History of Engineering Impacts on Biotechnology

SBE Webinar

Sep 27, 2012

Harvey Blanch

This webinar will focus on how biochemical engineering developed in response to the need for large-scale production of antibiotics in the 1940s and 50s, even though fermentation provided a route to many industrial organic chemicals prior to their production from petroleum.

Society for Biological Engineering (SBE)

SBE is a global technological community that promotes the integration of engineering with biology and realize its benefits through bioprocessing, biomedical, and biomolecular applications. SBE provides opportunities for interaction of engineers and scientists, develops products and services bring value to the broad biological engineering community, and infuses awareness of biological engineering among all functions and activities of AIChE.

Food, Pharmaceutical & Bioengineering Division (FP & BE)

The FP&BE division coordinates AIChE's activities in the fields of food, pharmaceuticals, and bioengineering.

Forest Bioproducts Division (FBP)

The Forest Bioproducts Division promotes knowledge sharing and networking on topics dealing with products obtained from forest resources and other lignocellulosic materials.

The Influence of Crystals, Particles and Powders On the Performance of Dry Powder Inhalers

Oct 19, 2011

Jag Shur

This presentation focuses on some key developments in understanding the relationships between the governing properties of DPIs and how these properties can be harnessed to develop designer formulation systems for DPIs.

Model-Based Characterisation of Organic and Aqueous Tablet Film Coating Processes: Parameter Estimation and Risk Management

Oct 19, 2011

Mark A. Pinto

Tablet coating is an important processing step in the pharmaceutical industry in which tablets are coated with an aqueous or organic film coating for both aesthetic and functional reasons. Mathematical models of tablet film coating are important in pharmaceutical development as they aid in design...

Study On Thermo-Bio-Chemical Biorefinery: Fast Pyrolysis of Lignocellulosic Biomass After Hydrolysis Pre-Treatment

Oct 19, 2011

Rene Garrido

Study on Thermo-Bio-Chemical Biorefinery: Fast Pyrolysis of Lignocellulosic Biomass After Hydrolysis Pre-treatment Rene Garrido, Nydia Ruiz-Felix, and Justinus Satrio Chemical Engineering Department, Villanova University, PA 19085 Abstract Biomass-based energy is a renewable source of energy from...

Optimization of a Wild-Type Mesophilic Clostridium Species That Produces Butanol

Oct 19, 2011

Jianzhong He

Optimization of a wild-type mesophilic Clostridium Species that produces butanol Fengxue Xin, Sandhi Eko Bramono, and Jianzhong He* (*Email: jianzhong.he@nus.edu.sg ) The raising energy demands and climate changes have stimulated people to look for sustainable energy. Among the alternatives,...

Effects of Ammonia Substitution On Stability Limits and Emissions of Premixed Hydrogen/Air Flames

Oct 19, 2011

Dong Hyun Um

The potential of partial ammonia (NH 3 ) substitution to improve the safety of hydrogen (H 2 ) use was evaluated, using premixed NH 3 /H 2 /air flames at normal temperature and pressure generated on a tube type burner. The effects of NH 3 substitution on the stability limits and nitrogen oxide (NO...

New Model-Based Platform for Enhanced Content Uniformity Prediction of Oral Dosage Forms

Oct 19, 2011

Salvador García-Muñoz

New Model-based Platform for Enhanced Content Uniformity Prediction of Oral Dosage Forms Being a critical quality attribute for capsules and tablets, content uniformity (CU) has received continued attention from practitioners and academics with multiples proposals to relate it with upstream...

Simultaneous Extracellular Polymeric Substance (EPS) and Lipid Production by Activated Sludge Via Fermentation of Glucose

Oct 19, 2011

Patrisha J. Pham

The use of activated sludge microflora to convert sugars, derived from the hydrolysis of lignocellulose biomass, into lipids for biofuel production is of current research interest in our group. Lipid accumulation in this system has been enhanced by manipulating the carbon-nitrogen (C:N) ratio and...

Modified AnoporeTM Hybrid Membranes for the Microfiltration of Cellulose Acid Hydrolysis Mixtures

Oct 18, 2011

Yong-Hong Zhao

Three classes of nonfouling substances, poly[poly(ethylene glycol) methyl ether methacrylate] (POEM), poly(sulfobetaine methacrylate) (PSBMA), and perfluoroalkyl tagged poly(ethylene glycol) surfactants (fPEG), were covalently tethered onto the surface of Anopore TM membranes (nominal pore size 0.2...

Heterogeneous Catalysts in the Dehydration of Fructose to HMF

Oct 18, 2011

Sylvia Reiche

Several crucial steps in the upgrading of biomass-derived raw materials involve acid catalyzed reactions, such as the hydrolysis of cellulose or the dehydration of sugars. Although heterogeneous catalysts are desired in large scale industrial processes, their application is limited by several...

Cellulase Inhibition by Pretreatment-Released Biomass Degradation Products

Oct 18, 2011

G. Peter van Walsum

The influence of pretreatment chemistry and the severity of dilute acid pretreatment on the subsequent enzymatic hydrolysis of soluble oligomer-derived and insoluble crystalline cellulose using a commercial enzyme preparation (Novozymes) was investigated. A dilute acid pretreatment was performed on...

Evaluation of Membrane Separations Opportunities within Lignocellulosic Biorefining Processes: Tailoring Membrane Properties

Oct 18, 2011

Jennifer M. Leberknight

Evaluation of Membrane Separations Opportunities within Lignocellulosic Biorefining Processes: Tailoring Membrane Properties Jennifer Leberknight, Amitkumar Gautam, and Todd J. Menkhaus South Dakota School of Mines and Technology Department of Chemical and Biological Engineering 501 East Saint...

Alkaline Deacylation of Corn Stover to Reduce Toxicity of Prehydrolyzates and Improve Enzymatic Hydrolysis

Oct 18, 2011

Urvi D. Kothari

Hydrolysates from dilute acid pretreatment of biomass contain various biomass degradation products which are inhibitory to enzymes and toxic to microorganisms. One of the main inhibitory compounds is acetic acid which is released from the lignin-hemicellulose matrix in the biomass. Acetic acid at...

Mechanistic Investigation of Drug Release From Asymmetric Membrane Tablets

Oct 18, 2011

Mary T. am Ende

An asymmetric membrane (AM) tablet was developed for a soluble model compound to study the in vitro drug release mechanisms in challenge conditions, including osmotic gradients, concentration gradients, and under potential coating failure modes. Porous, semipermable membrane integrity may be...

Lignin Depolymerization and Deoxygenation In Ionic Liquids

Oct 18, 2011

Blair J. Cox

Lignin, an amorphous aromatic biopolymer that comprises up to 30% of plant matter, was dissolved and depolymerized in ionic liquids under acidic conditions. The acidic ionic liquid 1-methylimidazolium chloride (HMIMCl) acts as a combination solvent and catalyst that facilitates degradation of...

Which Fractionation Process Can Overcome Techno-Economic Hurdles of a Lignocellulosic Biorefinery?

Oct 18, 2011

Adriaan van Heiningen

Lignocellulosics are considered as feed stock for transportation fuels and chemicals because they address two pressing global issues; climate change and “peak oil”. The collection and processing of wood at centralized facilities is already practiced by the forest products industry. Therefore, the...

Understanding the Impact of the Properties of Raw Materials Onto Product Quality Using JR-PLS

Oct 18, 2011

Salvador García-Muñoz

Multiple proposals are found in literature to analyze the impact of raw materials onto product using data analysis. From the methods proposed, the L-PLS is the only method that not only considers the ratio in which ingredients are mixed, but also the physical properties of the lots of raw material...

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