Search form

Biological Engineering

Featured

Society for Biological Engineering (SBE)

SBE is a global technological community that promotes the integration of engineering with biology and realize its benefits through bioprocessing, biomedical, and biomolecular applications. SBE provides opportunities for interaction of engineers and scientists, develops products and services bring value to the broad biological engineering community, and infuses awareness of biological engineering among all functions and activities of AIChE.

Forest Bioproducts Division (FBP)

The Forest Bioproducts Division promotes knowledge sharing and networking on topics dealing with products obtained from forest resources and other lignocellulosic materials.

Explore related resources below or:

Engineering a Better Way to Heal Broken Bones

November
2010
SBE Special Section
Matthew B. Murphy
Integrating mesenchymal stem cells and biomaterials shows promise for treating traumatic skeletal injuries via bone tissue engineering.

SYNTHETIC SPIDER SILK PROTEINS AND THREADS

May
2012
SBE Special Section
Axel H. Leimer, Lin Römer, Nathalie Mougin, Ute Slotta
E. coli can be genetically engineered to mimic the complex natural process by which a spider makes the proteins that it uses to spin the fibers for its web. With additional processing, fibers with properties similar to those of natural spider silk...

The Blood-Brain Barrier and Drug Delivery

March
2013
SBE Special Section
William Olbricht
To maintain favorable conditions in the brain, the blood-brain barrier limits mass transfer across brain tissue. However, it also restricts the systemic delivery of compounds to treat neurological disorders. Several treatment alternatives to bypass...

Speeding the Design of Bioprocesses

May
2008
SBE Special Section
Andrew D. Tustian, Sunil Chhatre
These experimental and modeling techniques enable the rapid, cost-effective design and scale-up of biopharmaceutical manufacturing in an integrated fashion.

Integrating Single-Use Filtration Systems

January
2003
Special Section
Holly Haughney
Disposable filtration systems are gaiing popularity in the pharmaceutical arena. This article defines the equipment, specifications, applications and potential advantages of single-use filters and ancillary equipment.

Singapore: An Emerging Leader in Biomedical Sciences

October
2007
SBE Special Section
Miranda G. S. Yap, Niki S. C. Wong
With a heavy investment in biomedical research— particularly the $330 million to build Biopolis in 2003— Singapore is seeing the fruits of its labor blossom.

Scaling Up Research to Commercial Manufacturing

November
2010
SBE Special Section
Erika Lapinskas
The production of stem-cell-based therapeutic products in large quantities is more complex than manufacturing molecular drugs. Scale-up and scale-out challenges arise related to the type of stem cell, cell expansion and banking, sterile handling,...

ONE-STEP FERMENTATIVE PRODUCTION OF POLYLACTIC ACID

May
2012
SBE Special Section
Min Kyung Kim , Sang Yup Lee, Si Jae Park
The use of PLA has been hindered by its complex and expensive synthesis process. A new technology promises to change this — giving PLA a chance to compete with fossil-based plastics.

Bioactive Devices: Uniting Form with Function

March
2013
SBE Special Section
Sujata Bhatia
Bioactive implants that combine a medical device with one or more biologic therapeutic agents show promise for the targeted treatment of complex medical conditions. Implantable medical devices, such as stents, grafts, and joint replacements, are...

Consider Using Fluoropolymers in Biological Applications

December
2004
Materials
Lauri Jenkins, Sharon Libert, Victor Lusvardi
Even with the use of costly corrosion-resistant alloys, metal contamination continues to occur in the biologics industry, thus reducing product yield and activity. Fluoropolymers are emerging as a viable solution to this problem.

Recombinant Protein Therapeutics from CHO Cells -- 20 Years and Counting

October
2007
SBE Special Section
Karthik P. Jayapal, Katie F Wlaschin, Wei-Shou Hu and Miranda G. S. Yap , Wei shou Hu
The CHO cell is at its height of technological prominence thanks to its adaptability to various culture conditions and plasticity in the context of genetic alterations. With further research, the application ofCell Culture Strategies based on...

Developing Cell Therapy Biomanufacturing Processes

November
2010
SBE Special Section
Jon A. Rowley
Establishing scalable technology platforms that allow for varying levels of production throughout the different stages of clinical testing can minimize process development timelines, drug-comparability risks, and — ultimately — costs.

RHEOLOGICAL CHARACTERIZATION OF BIO-BASED MATERIALS

May
2012
SBE Special Section
D. Bhopatkar, O.H. Campanella, P.H.S. Santos
Experimental and analytical tools combined with computational studies can be used to design new bio-based materials tailored for specific applications.

Pages

Subscribe to Biological Engineering