Biological Engineering

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Society for Biological Engineering (SBE)

SBE is a global technological community that promotes the integration of engineering with biology and realize its benefits through bioprocessing, biomedical, and biomolecular applications. SBE provides opportunities for interaction of engineers and scientists, develops products and services bring value to the broad biological engineering community, and infuses awareness of biological engineering among all functions and activities of AIChE.

Forest Bioproducts Division (FBP)

The Forest Bioproducts Division promotes knowledge sharing and networking on topics dealing with products obtained from forest resources and other lignocellulosic materials.

Bioprinting: Directed Tissue Self-Assembly

December
2007
SBE Special Section
Vladimir Kasyanov, Roger Markwald, Vladimir Mironov
Imagine eliminating patient waiting lists for organ transplants. Bioprinting holds the promise of making this happen, but, must research must be done first.

Keys to Bioreactor Selection

March
2002
Reactions and Separations
John A. Williams
A few basic types of bioreactor designs are used to produce a wide range of products, from antibiotics to foods to fuels. Here's how to pick the best options for your application.

Stem Cell Engineering 101

November
2010
SBE Special Section
Jonathan Monk
Stem cells are poised to transform medical treatments for a host of diseases and malignant conditions. Translating stem cell research into clinical therapies, disease models, and drug-screening platforms will require a combination of sound science...

Avoid the Pitfalls of Bioprocess Development

August
2006
Process Development
Mukesh Doble
This article presents the challenges that an engineer might encounter when designing or scaling up bioprocesses and offers practical solutions, including those cited in literature.

Your Personal Genome for $1,000?

November
2009
SBE Special Section
IBM scientists from four fields — nanofabrication, microelectronics, physics and biology — are collaborating to develop a “DNA transistor” that could make obtaining a personalized genome analysis easier, faster, and cheaper — ultimately as low as $...

Deciphering the Mechanisms of Therapeutic Protein Production

October
2007
SBE Special Section
Daniel W. Allison, Christoph L. Bausch, Trissa Borgschulte, Matthew V. Caple, Kevin J. Kayser
Demand for therapeutic recombinant proteins will eventually exceed current production capabilities. This is a major driver in further understanding Chinese Hamster Ovary (CHO) cell biology, which is the cell line of choice for producing these...

Fermentation Goes Large-Scale

January
2003
Special Section
Aristos Aristidou , J. J. Hahn , Pim van Hoek , Alex Patist
Designing an economically competitive and environmentally sustainable fermentation route means considering the downstream separations needed to capture the final product during the initial process design.

Purifying Therapeutic Monoclonal Antibodies

May
2008
SBE Special Section
Jace Fogle, Nuno Fontes, Benedicte Lebreton, Amy Len, Amit Mehta, Robert van Reis, Roshan Shrestha, Martha Lovato Tse, Bradley Wolk
Eliminating the affinity chromatography step in the mAb purification process trims equipment requirements, shrinks the plant footprint— and reduces costs.

Principles of Bioprocess Control

November
2009
SBE Special Section
Joseph S. Alford
The use of complex living organisms, process variation, and lack of real-time measurements of key parameters are some of the challenges involved in automating a bioprocess. This article explains an indirect approach to monitoring and controlling a...

Chemical Engineering in the Pharmaceutical Industry: R&D to Manufacturing

October, 2010
This book deals with various unique elements in the drug development process within chemical engineering science and pharmaceutical R&D. The book is intended to be used as a professional reference and potentially as a text book reference in pharmaceutical engineering and pharmaceutical sciences...
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