AIChE

Using Genomic Tools to Improve the Production of Biologics

November
2009
SBE Special Section
Nitya M. Jacob, Wei-Shou Hu, Bernard Liat Wen Loo, and Miranda Yap , Wei-Shou Hu
Recombinant DNA technology transforms mammalian cells into factories for protein-based therapeutics. New techniques provide chemical engineers with a better understanding of the process as well as the cells themselves.

Developing Cell Therapy Biomanufacturing Processes

November
2010
SBE Special Section
Jon A. Rowley
Establishing scalable technology platforms that allow for varying levels of production throughout the different stages of clinical testing can minimize process development timelines, drug-comparability risks, and — ultimately — costs.

Managing Dust Explosion Hazards

August
2009
Safety
Vahid Ebadat
Companies that handle powders or other particulate solids need to be aware of the potential for fire and explosions, and follow industry best practices, codes and standards to manage the risk.

Using Automation to Produce Quality Pharmaceuticals

October
2011
Instrumentation
Joseph S. Alford, P.E.
Automation can pay large dividends in the form of reduced process cycle times, lower operational costs, and more-consistent processes for manufacturing high-quality pharmaceutical products.

Select the Best Model for Two-Phase Relief Sizing

May
2001
Safety
Ron Darby, Paul R. Meiller, & Jarad R. Stockton , Ronald Darby
A variety of methods exist for sizing valves, but not all give the best predictions for certain conditions. RonDarby-PaulR.Meiller-JaradR.Stockton-

Use TRIZ in Reverse to Analyze Failures

May
2005
Career Catalyst
Jack Hipple
Asking “how could I make this fail?” can help you to identify potential problems that you might not otherwise have considered.

Bringing a Star to Earth

April
2009
Special Section
Bond Calloway, Jan Berry
An international R&D effort to build a fusion reactor and demonstrate the feasibility of fusion power is underway.

Handle Bulk Solids Safely and Effectively

September
2009
Fluids and Solids Handling
Eric Maynard, Greg Mehos and Eric Maynard
Follow these guidelines for proper design of bins, hoppers, and feeders to avoid operational and safety problems.

CEP: Journal Highlight - ChemEs get Schooled in Sustainability

August
2012
Journal Highlight
David T. Allen- University of Texas at Austin, David R. Shonnard- Michigan Technological University
Sustainable design will be required if the world is to support a growing population with increasingly higher living standards.

Optimize Process Regulation

December
2001
Instrumentation
Phillip D. Schnelle
Laboratory feedback proportional-integral control integrates statistical process control with automatic process control to minimize process variability.

Is Your Dust Collection System An Explosion Hazard?

October
2003
Safety
Vahid Ebadat
The prevalence of dust explosions in dust collection units may be due to the fact that the hazards posed by the powders handled are not fully understood or that explosion preventive and protective control measures are insufficient or absent. This...

Energy Research: Following the Money

July
2010
Special Section
Bond Calloway
Surveys of the energy-related papers presented at AIChE’s annual meetings shed light on the funding pathways for energy research by chemical engineers.

Employment of Chemical Engineers

January
2002
Special Section
Freeman Self, Freeman Self 
An analysis of past employment data can help identify future trends in chemical engineering. FreemanSelf-EdEkholm-

CEP: News Update

August
2012
News Update
Updates Include: The Natural Gas Debate Continues Smart Material Stays Cool in the Heat Firefly-Semiconductor Hybrid Lights Up Ionic Liquid Improves Hydrogen-Producing Catalyst One-Pot Synthesis Yields Zeolites at Bargain Prices High-Carbon Diet...

Applications in Drug Delivery and Tissue Engineering

February
2006
SBE Special Section
Ali Khademosseini, Robert Langer
Nanotechnology is an emerging field that could potentially make a major impact on human health. Nanomaterials promise to revolutionize medicine and are increasingly used in drug delivery or tissue engineering applications.

The Road to Sustainability

June
2007
Special Section
Darlene Schuster
What are some of the resources available to support industry's implementation of sustainability?

Fundamentals of Industrial Catalytic Processes, 2nd Edition

October, 2005
Catalysis is central to the chemical industry, as it is directly or involved in the production of almost all useful chemical products. In this book the authors, present the definitive account of industrial catalytic processes. Throughout Fundamentals of Industrial Catalytic Processes the...

Nanotechnology: Cause for Concern?

September
2007
News Feature
Kristine Chin
Nanotechnology— it's a small science with big stakes. Some of the unique properties that make nanoscale materials useful may also pose hazards to humans and the environment. Can the EPA find a way to effectively regulate these tiny high-tech...

Saluting AIChE’s Centenarians

November
2008
Centennial
In honor of AIChE’s 100th birthday, we recognize two members who have each celebrated more than 100 birthdays.

Valves 101: Types, Materials, Selection

March
2009
Back To Basics
Brian Gordon
The most common valves used in chemical processing are ball valves, butterfly valves, diaphragm valves, and check valves.

Co-Inventors: Who Owns the Patent Rights?

June
2012
Patent Update
M. Henry Heines
A joint invention arises from the combined efforts of two or more inventors. Once a patent is granted, however, the inventors do not necessarily share in the rewards.

Science on a World Stage

July
2008
News Feature
Gordon Ellis
The first annual World Science Festival takes Manhattan by storm, with 120,000 people celebrating scientific diversity.

Virtualizing Your Process Control Computers

January
2012
Instrumentation
Paul Hodge
By employing the latest virtualization solutions for process control systems, chemical plants can reduce PC hardware requirements, simplify system management, and lower the total cost of ownership, as well as improve site availability, reliability,...

Whatever Happened to the Class of 2009?

September
2009
News Feature
Gordon Ellis
Regardless of their current employment status and personal outlook, the new class of chemical engineering graduates is con?dent that they possess a unique versatility and capacity to make good and do good.

Classifying Reactive Chemicals

March
2004
Safety
M. Sam Mannan, Sanjeev R. Saraf, William J. Rogers
This simple classification scheme can be used to characterize the thermal instability risks posed by reactive chemicals in a process.

Audit Your New EHS Software System

October
2004
Environmental Management
Jill Barson Gilbert
A post-implementation audit of the environmental, health and safety management information system evaluates how well the software meets user needs and its value to the organization.

Measuring Temperature by Direct Contact

September
2011
Back To Basics
Gary Freemer
Thermocouples and resistance temperature detectors are the most common contacting temp­erature sensors. Understand the techniques and apply them correctly to increase your temperature measurement accuracy.

Properly Purge and Inert Storage Vessels

February
2001
Safety
George R. Kinsley Jr.
Inert gases are used to prevent fires and explosions in the vapor spaces of equipment. Correct selection of oxygen concentration and inert gas flow rate are critical to ensuring safety.

Minimize Enforcement Penalties

July
2001
Environmental Management
Jessica L. Idzerda
Identify possible New Source Review/Prevention of Significant Deterioration penalties by conducting an internal audit and disclosing potential violations.

Preventing Pollution Around the World

November
2001
Environmental Management
J. J.  Rao
By implementing these strategies at all of its overseas facililities, an international corporation can reap such benefits as increased efficiency, reduced costs and a positive public image.

Choose the Right Gas Sensor

September
2009
Instrumentation
Sandra Barnes
Selecting a sensor for continuous monitoring involves many considerations. This article discusses the types of sensors available, their applicability and limitations, and how to choose an appropriate sensor to protect people and equipment.

Improving Reverse Osmosis Performance

September
2010
Reactions and Separations
Loraine Huchler
Follow these guidelines for monitoring, evaluating, and troubleshooting RO units to ensure reliable and efficient system operation.

Process Synthesis: Poised for a Wider Role

April
2001
On The Horizon
W. R. Johns
Software for generating process designs has made relatively limited inroads so far. But, it now is set to follow simulation and become a tool routinely used by chemical engineers.

Test Your Incinerator Knowledge

February
2003
Environmental Management
Richard J. Martin
Do you feel like you're in the dark? Take this quiz to find out how much you know about thermal oxidizer selection and operation.

Exploring Instrumentation Alternatives

September
2008
Instrumentation
Robert Baker
Salvaged, remanufactured, refurbished or new-surplus equipment may be a cost-effective option. Here's how to recognize when such devices may no longer meet safety or regulatory requirements.

Should Your Organization Fly Warning Flags?

December
2009
Safety
Ian Sutton
In the safety culture of some companies, the first recognition of trouble may be a sudden and massive failure. Learn how to decipher the warning signals to avoid safety incidents. <BR><BR>

Agitating Fibrous Materials

June
2010
Back To Basics
Gregory T. Benz
Slurry agitation involves complicated processes. This article presents guidelines for understanding the rheology of cellulosic and other fibrous materials, and outlines a method for scaling up their agitation.
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