AIChE

One of the important challenges in effective real time process management is the implementation of intelligent systems that can assist human operators in making supervisory control decisions, instead of simply sounding an alarm when process variables go out of range. Operator failures to exercise...

The Wurster column coating process of pharmaceutical solids has been studied for many years and a considerable body of literature has been produced covering various aspects of the process. To achieve uniform active coating content is one of the key interests for the pharmaceutical manufacturing...

Energy Storage Layouts for Concentrated Solar Plants ? A comparison of Process Control Flavio Manenti 1,* , Zohreh Ravaghi-Ardebili 1 , Giovanni Manenti 2 1 Politecnico di Milano, Dipartimento di Chimica, Materiali e Ingegneria Chimica ?Giulio Natta?, Piazza Leonardo da Vinci 32, 20133 Milano 2 FBM...

This talk is part of the invited session 'Random Thoughts: Inspired by Rich Felder'. Description: This session honors Dr. Richard M. Felder, Hoechst Celanese Professor Emeritus of Chemical Engineering at North Carolina State University. Rich has been recognized for his sustained contributions to...

This presentation considers the characterization of the set of allowable real parameter uncertainties for the output of a nonlinear system to be located in a prespecified target range. This word “parameter” is used by FDA and in this presentation to refer to any variable held at a fixed value...

As an emerging technology, THz spectroscopy has gained increasing attention in the pharmaceutical area during the last decade. This attention is due to the fact that (1) it provides a promising alternative approach for in-depth understanding of both intermolecular interaction among pharmaceutical...

The future of the global nuclear energy industry, while certainly not without its challenges, remains vibrant. Even as the industry contends with near-record-low natural gas prices and the accident at Fukushima Daiichi, the reality is that global demand for electricity and concern over carbon...

QbD and PAT requires the next generation of pharmaceutical products be manufactured through continuous processing integrated with online monitoring tools coupled with efficient automatic model-based feedback control system to achieve the precise control of process variables so that the predefined...

Previous work in understanding the thermodynamics of the film coating operation has focused mainly around the pseudo-steady state reached between the drying air and the cooling effect from the evaporation of the spraying solution [1]. The work presented here aims to mathematically describe the time...

Fossil fuels currently comprise more than 80 percent of global (and U.S.) energy consumption and are expected to continue to play a critical role in meeting the world’s energy needs for the foreseeable future. Making use of these fuel sources in a cost-effective and environmentally sustainable...