Pharmaceutical Engineering & Drug Delivery

CEP: News Update

July
2014
News Update
Nanoparticles Detect Sulfur Content in Crude Oil; Putting Waste Heat to Work; New Process Prints Personalized Drugs; EPA to Cut CO2 from Power Plants; Microbes Convert Biodiesel Waste into Valuable Chemicals

CEP: News Update

March
2014
News Update
Silicon Anode Gets a Fruity Makeover; New Anode Provides a Home for Plus-Sized Na+ Ions; A Flicker of Hope for Nonflammable Li-Ion Batteries; Bio-Inspired Glass Is Bendable; and more.

SBE Update: Drug Delivery and Chemical/Biological Engineering

March
2013
SBE Special Section
June Wispelwey
Although you might not associate drug delivery with chemical engineering, the principles of chemical engineering — such as mass and energy balances, transport phenomena, reaction kinetics, and particle technology — are intimately involved in drug...

Introduction to Drug Delivery Technology

March
2013
SBE Special Section
John T. Santini, Jr.
Drugs can be administered by many routes, yet all emerging drug delivery technologies aim to improve drug efficacy, minimize side effects, and reduce the burden of care for patients and physicians.

Engineering Biodegradable Nanoparticles for Drug and Gene Delivery

March
2013
SBE Special Section
Junwei Zhang, W. Mark Saltzman
Engineered nanoparticles can deliver therapeutic agents to specifically targeted cells and then release those agents in a precisely controlled manner. Improved pharmacokinetic properties, reduced toxicity, and the ability to cross biological barriers are some of the key benefits of this approach.

The Blood-Brain Barrier and Drug Delivery

March
2013
SBE Special Section
William Olbricht
To maintain favorable conditions in the brain, the blood-brain barrier limits mass transfer across brain tissue. However, it also restricts the systemic delivery of compounds to treat neurological disorders. Several treatment alternatives to bypass...

Bioactive Devices: Uniting Form with Function

March
2013
SBE Special Section
Sujata Bhatia
Bioactive implants that combine a medical device with one or more biologic therapeutic agents show promise for the targeted treatment of complex medical conditions. Implantable medical devices, such as stents, grafts, and joint replacements, are...

Building a Better Biofuel Production Platform

AIChE Annual Meeting
Oct 17, 2011
Building a Better Biofuel Production Platform: Engineering metabolic control techniques to control the photosynthetic cyanobacterium Synechocystis sp...

QbD In Dry Powder Inhaler Development

AIChE Annual Meeting
Oct 19, 2011
Summary Developing products comprising un-bound fine cohesive powders throws up significant challenges. Dry powder inhalers present a prime example...

Managing Uncertainty In Design Space

AIChE Annual Meeting
Oct 19, 2011
Design of experiments, followed by numeric and graphical optimization, is frequently used by engineers to optimize a process, and to define a design...

QbD for Generic MR Drug Products

AIChE Annual Meeting
Oct 18, 2011
The Office of Generic Drugs ensures the therapeutic equivalence and quality of generic drug products. This is based principally upon a regulatory...

Quality by Design for Generic Drugs

AIChE Annual Meeting
Oct 17, 2011
To facilitate the implementation of Quality by Design (QbD) for abbreviated new drug application (ANDA), Office of Generic Drugs (OGD) has developed...

FDA Perspective On QbD for Analytical Methods

AIChE Annual Meeting
Oct 17, 2011
QbD is a systematic approach to pharmaceutical development and product lifecyclemanagement. QbD provides new opportunities and modern tools to...

QbD - It's Not Just for Breakfast Anymore

AIChE Annual Meeting
Oct 16, 2011
We are approaching the ten-year mark for the Quality by Design initiative in the pharmaceutical industry. Much has been accomplished and demonstrated...

Mixture DOE and Design Space

AIChE Annual Meeting
Nov 10, 2010
Present a case study on mixture DOE involving five components used to formulate a pharmaceutical tablet. The goal is to achieve a sustained release...
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