Molecular, Cellular, & Tissue Engineering
From Biomass to Biofuels: Breaking the Cellulose Barrier
Cellulases are of considerable current interest for converting the cellulosic content of biomass to fermentable sugars for biofuels production.
Tumor Targeting Theory: Physiological Limits from Scaling Analyses, and Design Principles for Better Magic Bullets
For the past two decades the capability of protein engineers to devise clever tumor-targeting molecules has outstripped our understanding of how these agents distribute through the body and permeate through tumors.
Biomaterials for Stem Cell Tissue Engineering
Stem cells have become a promising cell source in the tissue engineering field.
Towards Genome Engineering in Chinese Hamster Ovary Cells
Worth over $30 billion, therapeutic proteins, produced by recombinant mammalian cells, have been the fastest growing class of medicines in industrialized nations.
Breaking the Cell Wall Barrier for Difficult-to-Express Natural and Supernatural Products
Modern recombinant DNA expression technologies, by definition, challenge cells to engage in unnatural acts; specifically, the production of new types and large quantities of proteins for which the cells have not evolved.
Molecular Bioprocessing as a New Paradigm for Drug Discovery
The drug discovery process is expensive and often inefficient. With the emergence of genomic and proteomic information, the growth of critical molecular targets is rapid.
Molecular Elucidation and Engineering of Stem Cell Microenvironments
Stem cells are defined by their capacities for self-renewal and differentiation into one or more cell lineages, and these processes are regulated by signals from the stem cell microenvironment, or niche, in various tissues throughout organismal de
A Bottom Up Approach to Systems Biotechnology – Lessons Learned from Bacterial Signal Transduction
Bacterial quorum sensing offers an interesting viewpoint from which to study and control cell phenotype.











