Biosensors / Devices

One of the key challenges in the field of synthetic biology is to engineer not only single cells but also communities of cells that exhibit coordinated, population level behaviors. Synthetic biologists have employed components from acyl-homoserine lactone (AHL)-based quorum-sensing (QS) systems in...

The objective of the present study is to integrate the information on intracellular signaling network structures with large-scale gene expression data sets to predict functional changes in the cellular pathways that are operational under those conditions. Conventional approaches do not consider the...

An important topic in systems biology is to understand the dynamic properties of the biological networks. Previous studies have provided important insights into the mechanistic principles of dynamic behaviors by applying kinetic modeling to condition-specific and very small networks. However, it...

Targeted protein degradation in eukaryotic cells requires recruitment of the target protein to proteasome which is usually triggered by ubiquitination of the target protein. It has recently been shown that ubiquitination is not necessary and localization to the proteasome is sufficient for...

Rapid and accurate detection is the key to controlling the spread of viral pathogens. Recent advances in the field of surface enhanced Raman scattering (SERS) spectroscopy have demonstrated the utility of this technology in diverse research disciplines ranging from surface chemistry and...

Recently, Surface-enhanced Raman scattering (SERS) has attracted great attention because of its high sensitivity, label-free detection, and low detection limit. Additionally, it provides a specific fingerprint spectrum of multiplex samples with narrow band width. Because of these advantages, a...