Pharmaceutical Engineering & Drug Delivery

Designing Drug-Delivery Nanoparticles

September
2016
On The Horizon
Aaron Anselmo, Samir Mitragotri
Nanoparticles for drug delivery can be better designed by modeling the body as unit processes connected by the vascular system. Each organ and organ function can be represented as a unit process on organ-on-a-chip devices.

On the Modeling of Oral Drug Delivery

Conference Presentation
AIChE Annual Meeting
Thursday, November 1, 2012 - 12:30pm-1:00pm
On the Modeling of Oral Drug Delivery Naresh Pavurala, Luke E.K Achenie Department of Chemical Engineering, Virginia Polytechnic Institute and State...

QUALITY by Design (QBD), Biopharmaceutical Manufacture

Conference Presentation
AIChE Annual Meeting
Monday, October 17, 2011 - 8:00pm
In the biopharmaceutical industry, consistently manufacturing a safe and high quality protein drug substance can be challenging. Recently, a...

CEP: News Update

May
2016
News Update
Building Microstructures, One Particle at a Time As engineers and scientists synthesize ever-smaller structures, one source of building blocks is colloidal particles. Now, a new method enables the creation of colloidal particle structures with...

AIChE Graduate Research Spotlight - Dec. 2015

Archived Webinar
Dec 15, 2015
Three AIChE graduate student members who recently published their graduate level research joined us on this first webinar of our Graduate Research...

Engineering Global Biological Solutions

Conference Presentation
AIChE Annual Meeting
Monday, November 17, 2014 - 11:15am-12:15pm
The past decades have seen biopharmaceuticals begin to dominate the drug development pathway and already we can see potent biologics bringing...

Automation and Control of Drug-On-Demand Technology

Conference Presentation
AIChE Annual Meeting
Wednesday, October 31, 2012 - 5:15pm-5:45pm
Stimulated by initiatives such as PAT and QbD, the pharmaceutical industry has been focusing on the development of innovative, efficient...

A QbD Approach to the Process Development of Tofacitinib

Conference Presentation
AIChE Annual Meeting
Wednesday, October 31, 2012 - 1:15pm-1:30pm
Tofacitinib citrate (CP-690,550-10) is currently being evaluated for the treatment of rheumatoid arthritis, psoriasis and other diseases. An NDA has...

Optimal Design of Transient Microreactor Experiments

Conference Presentation
AIChE Annual Meeting
Tuesday, October 30, 2012 - 12:30pm-1:00pm
Development of synthetic routes for active pharmaceutical ingredient (API) synthesis is increasingly performed using microreactors, because their use...

A Novel QbD Tool for Statistical Data Analysis

Conference Presentation
AIChE Annual Meeting
Tuesday, October 30, 2012 - 10:15am-10:30am
One of cornerstones of Quality by Design (QbD) is Design of Experiments (DoE). However, in addition to DoE, ICH Q8 (R2) recommends an enhanced...

Modelling of a Filter Drying Process

Conference Presentation
AIChE Annual Meeting
Monday, October 29, 2012 - 5:15pm-5:45pm
Filter drying, also referred to as vacuum contact drying, is a process widely used in the pharmaceutical industry to remove water or organic solvents...
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