Pharmaceutical Engineering & Drug Delivery

CEP: News Update

January
2016
News Update
Hybrid Material Delivers a One-Two Punch Gold and palladium are both valuable metals, for different reasons. Palladium is known for its catalytic ability, and gold for its plasmonic properties. Bifunctional Catalyst Upgrades Ethanol to Butanol...

Pharma Turns to Gut for New Drugs

January 25, 2016
The past few years have been full of stories about how a number of serious conditions could be treated or cured by introducing certain bacteria to the digestive system. Now, a...

Bioactive Devices: Uniting Form with Function

March
2013
SBE Special Section
Sujata Bhatia
Bioactive implants that combine a medical device with one or more biologic therapeutic agents show promise for the targeted treatment of complex medical conditions. Implantable medical devices, such as stents, grafts, and joint replacements, are...

SBE Update: Drug Delivery and Chemical/Biological Engineering

March
2013
SBE Special Section
June Wispelwey
Although you might not associate drug delivery with chemical engineering, the principles of chemical engineering — such as mass and energy balances, transport phenomena, reaction kinetics, and particle technology — are intimately involved in drug...

The Blood-Brain Barrier and Drug Delivery

March
2013
SBE Special Section
William Olbricht
To maintain favorable conditions in the brain, the blood-brain barrier limits mass transfer across brain tissue. However, it also restricts the systemic delivery of compounds to treat neurological disorders. Several treatment alternatives to bypass...

Sustainability in (Bio)Pharmaceuticals

August 30, 2012
This meeting will bring together thought-leaders from the pharmaceutical and biopharmaceutical industries. The meeting's goal is to allow engineers in these industries to assess...

Creating an Internet for Genomic Information

December 24, 2014
A group called the Global Alliance for Genomics and Health (known as the Global Alliance ) wants to maximize the use of genetic data by creating a responsible way to share it with...

CEP: AIChE Journal Highlight - Layer-by-Layer Approach Enables Customizable Medication Therapy

April
2015
Journal Highlight
In the April AIChE Journal Perspective article, “Layer-by-Layer Approaches to Staging Medicine from Surfaces,” Paula T. Hammond of the Massachusetts Institute of Technology describes her research on a method that creates layers of thin films stacked on top of one another. Each layer contains a different therapeutic, which is incorporated into the thin film via one of several mechanisms (e.g., charge, hydrogen bonding, or other complementary interaction). This technique is useful for drug therapy in applications such as bone regeneration.

Engineering Global Biological Solutions

Conference Presentation
AIChE Annual Meeting
Monday, November 17, 2014 - 11:15am-12:15pm
The past decades have seen biopharmaceuticals begin to dominate the drug development pathway and already we can see potent biologics bringing...

On the Modeling of Oral Drug Delivery

Conference Presentation
AIChE Annual Meeting
Thursday, November 1, 2012 - 12:30pm-1:00pm
On the Modeling of Oral Drug Delivery Naresh Pavurala, Luke E.K Achenie Department of Chemical Engineering, Virginia Polytechnic Institute and State...

Automation and Control of Drug-On-Demand Technology

Conference Presentation
AIChE Annual Meeting
Wednesday, October 31, 2012 - 5:15pm-5:45pm
Stimulated by initiatives such as PAT and QbD, the pharmaceutical industry has been focusing on the development of innovative, efficient...

A QbD Approach to the Process Development of Tofacitinib

Conference Presentation
AIChE Annual Meeting
Wednesday, October 31, 2012 - 1:15pm-1:30pm
Tofacitinib citrate (CP-690,550-10) is currently being evaluated for the treatment of rheumatoid arthritis, psoriasis and other diseases. An NDA has...

Optimal Design of Transient Microreactor Experiments

Conference Presentation
AIChE Annual Meeting
Tuesday, October 30, 2012 - 12:30pm-1:00pm
Development of synthetic routes for active pharmaceutical ingredient (API) synthesis is increasingly performed using microreactors, because their use...

A Novel QbD Tool for Statistical Data Analysis

Conference Presentation
AIChE Annual Meeting
Tuesday, October 30, 2012 - 10:15am-10:30am
One of cornerstones of Quality by Design (QbD) is Design of Experiments (DoE). However, in addition to DoE, ICH Q8 (R2) recommends an enhanced...

Modelling of a Filter Drying Process

Conference Presentation
AIChE Annual Meeting
Monday, October 29, 2012 - 5:15pm-5:45pm
Filter drying, also referred to as vacuum contact drying, is a process widely used in the pharmaceutical industry to remove water or organic solvents...
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