SBE Update: Drug Delivery and Chemical/Biological Engineering

March
2013
SBE Special Section
June Wispelwey
Although you might not associate drug delivery with chemical engineering, the principles of chemical engineering — such as mass and energy balances, transport phenomena, reaction kinetics, and particle technology — are intimately involved in drug...

Introduction to Drug Delivery Technology

March
2013
SBE Special Section
John T. Santini, Jr.
Drugs can be administered by many routes, yet all emerging drug delivery technologies aim to improve drug efficacy, minimize side effects, and reduce the burden of care for patients and physicians.

Engineering Biodegradable Nanoparticles for Drug and Gene Delivery

March
2013
SBE Special Section
Junwei Zhang, W. Mark Saltzman
Engineered nanoparticles can deliver therapeutic agents to specifically targeted cells and then release those agents in a precisely controlled manner. Improved pharmacokinetic properties, reduced toxicity, and the ability to cross biological barriers are some of the key benefits of this approach.

The Blood-Brain Barrier and Drug Delivery

March
2013
SBE Special Section
William Olbricht
To maintain favorable conditions in the brain, the blood-brain barrier limits mass transfer across brain tissue. However, it also restricts the systemic delivery of compounds to treat neurological disorders. Several treatment alternatives to bypass...

Bioactive Devices: Uniting Form with Function

March
2013
SBE Special Section
Sujata Bhatia
Bioactive implants that combine a medical device with one or more biologic therapeutic agents show promise for the targeted treatment of complex medical conditions. Implantable medical devices, such as stents, grafts, and joint replacements, are...

SBE Supplement: A Decade of Progress (Full 28-Page Supplement)

November
2014
SBE Special Section
Abigail Engelberth, Arpan Bandyopadhyay, Daniel Blashki, Eduardo Ximenes, Gauri Nabar, Gregory Stephanopoulos, Hsu-Yuan Fu, Jessica Winter, June Wispelwey, Kimberly Ogden, Matthew B. Murphy, Michael Ladisch, Nandita Vishwanathan, Nathan Mosier, Rachel M. Buchanan, Wei-Shou Hu
Celebrating a Decade of Progress in Biological Engineering; Genomics and Systems Biotechnology in Biopharmaceutical Processing; Block-Copolymer Nanocomposites for Biomedical Applications; Stem Cell Therapy for Regenerative Medicine; Biological Engineering and the Emerging Cellulose Ethanol Industry; Algae as a Bio-Feedstock.

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