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Producing Fuels and Chemicals from Lignocellulosic Biomass

August
2008
SBE Special Section
Mark Holtzapple, Rocio Sierra, Aaron Smith, Cesar Granda and Mark T. Holtzapple
As oil and natural gas prices rise, lignocellulosic biomass becomes a viable feedstock for the fuel and chemical industries— provided key issues are addressed.

Speeding the Design of Bioprocesses

May
2008
SBE Special Section
Andrew D. Tustian, Sunil Chhatre
These experimental and modeling techniques enable the rapid, cost-effective design and scale-up of biopharmaceutical manufacturing in an integrated fashion.

Purifying Therapeutic Monoclonal Antibodies

May
2008
SBE Special Section
Amit Mehta, Amy Len, Benedicte Lebreton, Bradley Wolk, Jace Fogle, Martha Lovato Tse, Nuno Fontes, Robert van Reis, Roshan Shrestha
Eliminating the affinity chromatography step in the mAb purification process trims equipment requirements, shrinks the plant footprint— and reduces costs.

Engineering Organs: Heart and Esophagus

December
2007
SBE Special Section
Buddy D. Ratner
The potential for tissue engineering to transform the practice of medicine is enormous. Chemical engineers will play important roles in this revolution.

Bioprinting: Directed Tissue Self-Assembly

December
2007
SBE Special Section
Roger Markwald, Vladimir Kasyanov, Vladimir Mironov
Imagine eliminating patient waiting lists for organ transplants. Bioprinting holds the promise of making this happen, but, must research must be done first.

Deciphering the Mechanisms of Therapeutic Protein Production

October
2007
SBE Special Section
Christoph L. Bausch, Daniel W. Allison, Kevin J. Kayser, Matthew V. Caple, Trissa Borgschulte
Demand for therapeutic recombinant proteins will eventually exceed current production capabilities. This is a major driver in further understanding Chinese Hamster Ovary (CHO) cell biology, which is the cell line of choice for producing these...

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