Biomanufacturing for Chemical Engineers

Photo courtesy of BTEC. Copyright 2012 North Carolina State University.
Photo courtesy of BTEC. Copyright 2012 North Carolina State University.
Course ID: 
ELA103
Course Type: 
eLearning (online) Course
Course Length: 
7 Hours

This course presents the fundamentals of biomanufacturing. It focuses on the unit operations utilized to manufacture biological drug products.  After an overview of product types, processes, and current Good Manufacturing Practice you’ll address the maintenance of cell lines and growth of cells in a bioreactor. Topics such as mass transfer, process control, and product expression are emphasized.  In the second half of the course, lectures focus on downstream unit operations that harvest cells, remove byproducts or contaminants, and fill the final bulk product.

This course was developed in conjunction with the Biomanufacturing Training and Education Center (BTEC) at NC State and SBE.

Topics will include:

  • Why and how biopharmaceutical production is regulated
  • Typical biomanufacturing flow
  • Cryopreservation
  • Basics of metabolism and nutrition requirements
  • Examples of yield calculations
  • Cell growth for industrial production
  • Non-suspension cultures
  • Solid-liquid separation
  • Gravity sedimentation vs. centrifugation
  • Centrifuge process and performance parameters
  • Chromatography techniques by separation mechanism
  • Viral clearance methods
  • The ultimate goal of ultrafiltration/diafiltration (UF/DF):
  • protein concentration, buffer exchange 
Continuing Education Units: 
0.7
Professional Development Hours
7.0 PDHs

Instructor(s)

Six instructors from the staff of the Biomanufacturing Training and Education Center (BTEC) at NC State University provided content for this course.

Pricing

AIChE / SBE Members $795
AIChE / SBE Grad Student Members $397.50
AIChE / SBE Undergrad Student Members $397.50
Non-Members* $995
Training 10 or More? Volume Pricing is available. Send an e-mail to

elearning@aiche.org for more information.

* AIChE membership is just $199 a year. For more information on becoming an AIChE / SBE member click here.

If you are interested in scheduling this course for In-Company Training, please complete the Request for Proposal Form and we will e-mail you a proposal.
 

Registration

Questions? Check out the Frequently Asked Questions or email us at edu@aiche.org

Related Topics: