Body-on-a-Chip -- A Tool for Predictive Pharmacology/Toxicology

In this presentation, Professor Mike Shuler details his work to understand the response of the human body to various pharmaceutical and environmental chemicals using a combination of whole body modules and micro models Professor Shuler’s research focuses on microfabricated devices combined with cell cultures. This combination provides a viable alternative to animal models to predict toxicity and response to pharmaceuticals. To date his models of the GI tract have been used to examine the response to oral exposure of drugs, chemicals, and nanoparticles. These coupled GI tract/body modules have been used to mimic human response to acetaminophen plus ethanol and have shown that nanoparticles can interfere with normal physiological responses such as iron uptake and nutrition. View this webinar to learn more about the exciting work being done in the field of predictive pharmacology.