Uwe Sauer
ETH Zurich
Uwe Sauer is Professor of Systems Biology in the Department of Biology at the ETH Zurich. He earned his M.S. and Ph.D. in microbiology from the University of Göttingen. During his postdoc work on metabolic engineering in the chemical engineering lab of Jay Bailey in Zurich, he became interested in computational modeling of cellular behavior and quantitative analysis of intracellular fluxes in particular. In the late 90ties, his research began to focus on quantitative understanding of interactions and regulation within complex microbial metabolic networks by using and developing cutting-edge experimental and computational methods. For this purpose, research in the Sauer lab takes an interdisciplinary approach that combines quantitative experimentation and modeling to solve fundamental questions of complex metabolic network operation, allowing to engineer general cellular functions such as redox and energy metabolism. In particular, his lab has pioneered methods for 13C-flux analysis and is a key player in quantitative metabolomics, such that he became a well-recognized expert on central metabolism of bacteria and yeast.
Dr. Sauer has over 70 publications in peer-reviewed journals over the last 5 years, and is a member of various international editorial boards, scientific steering and advisory committees of international organizations and companies in systems biology and biotechnology.