Stem Cell Engineering Conference Program
Sunday, January 20
Monday, January 21
Tuesday, January 22
Wednesday, January 23
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3:00pm-6:00pm |
Registration and Hotel Check-in |
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6:00pm-7:00pm |
Welcome Reception |
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7:00pm-7:15pm |
Introductory Remarks: David Schaffer, University of California, Berkeley |
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7:15pm-8:15pm |
Opening Keynote Address: "Histocompatible Pluripotent Stem Cells" George Daley, Boston Children's Hospital, Harvard University |
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8:15pm-10:00pm |
Dinner |
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7:00am-8:30am |
Breakfast |
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8:30am-10:30am |
Session 1: High Throughput and Microfluidic Screening Platforms |
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8:30am-9:10am |
Invited Speaker: Sangeeta Bhatia, Massachusetts Institute of Technology, "Engineering the Stem Cell Microenvironment: Microtechnology Tools for High-Throughput Analysis" |
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9:10am-9:30am |
Daniel G. Anderson, Massachusetts Institute of Technology, "Combinatorial Development of Biomaterials for Tissue Engineering and Drug Delivery" |
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9:30am-9:50am |
Tiago G. Fernandes, Rensselaer Polytechnic Institute, "A High Throughput 3D Cell Microarray to Study Stem Cell Fate" |
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9:50am-10:10am |
Shuichi Takayama, University of Michigan, "Microfluidics for Stem Cell Biology and Therapy" |
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10:10am-10:30am |
Edwin Monuki, University of California, Irvine, "Dielectric Differences among Neural Stem Cells and Their Progeny" |
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10:30am-10:50am |
Break |
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10:50am-12:30pm |
Session 2: Stem Cells and Drug Discovery: Pharmacology and Toxicology Screening Platforms |
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10:50am-11:30am |
Invited Speaker: Sheng Ding, The Scripps Research Institute, "A Chemical Approach to Stem Cell Biology" |
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11:30am-11:50am |
Jon Chesnut, Invitrogen, "Chromosomal Targeting in Embryonic Stem Cells Using the phiC31 Familay of Integrases: Stem Cells as Enabling Tools for Screening" |
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11:50am-12:10pm |
Joel Voldman, Massachusetts Institute of Technology, "Microscale Manipulation of Mouse Embryonic Stem Cells for Studying Cell Fusion-Mediated Reprogramming and Diffusible Signaling" |
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12:10pm-12:30pm |
Danny Van Noort, Institute of Bioengineering and Nanotechnology, "3D Cell Cultures in Microfluidics for Drug Discovery" |
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12:30pm-2:00pm |
Lunch |
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2:00pm-2:50pm |
Keynote Address: "Quantitative Systems Analysis of Signaling Networks Governing Cell Phenotype Behavior" |
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2:50pm-4:30pm |
Session 3: Systems-Based Approaches to Understanding Fate Decisions |
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2:50pm-3:30pm |
Invited Speaker: Christopher Chen, University of Pennsylvania, "Stem Cell Differentiation: Mechanical Forces Rhoa and Adhesion Signaling" |
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3:30pm-3:50pm |
Nicolas Plachta, California Institute of Technology, "Engineered Embryonic Stem Cells as a Discovery Tool in Neurobiology: Identification of Molecular Mechanisms of Axonal Degeneration" |
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3:50pm-4:10pm |
WeiJia Wang, University of Toronto, "A Multiparameter Flow Cytometric Assay to Investigate Cytokine Synergies during Erythroid Development" |
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4:10pm-4:30pm |
Babak Esmaeli-Azad, DNAmicroarray,Inc., San Diego, "Modeled Stem Cell Niche Assays Using Biomaterial Microarrays" |
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4:30pm-6:00pm |
Poster Session with Refreshments |
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7:00am-8:30am |
Breakfast |
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8:10am-10:10am |
Session 4: Intercellular Signaling and the Engineered Niche |
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8:10am-8:50am |
Invited Speaker: Peter Zandstra, University of Toronto, "Control of Auto-Regulatory Signaling to Modulate Embryonic Stem Cell Self-Renewal and Differentiation" |
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8:50am-9:10am |
Krishnendu Roy,The University of Texas at Austin, "Engineering Intercellular Signals of Thymic Niche: Towards Generation of Functional T Cells from Stem Cells" |
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9:10am-9:30am |
Eleftherios Sachlos, Harvard University, "Embryoid Body Shell Formation Reduces Diffusive Transport of Inductive Biochemicals" |
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9:30am-9:50am |
Basha Stankovich, University of California, Merced, "Role of Adhesion Molecules in Hematopoietic and Endothelial Commitment of Muring Embryonic Stem Cells" |
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9:50am-10:10am |
Natesh Parashurama, Harvard Medical School, "Activin Alters the Kinetics of Endoderm Induction in Embryonic Stem Cells Cultured on Collagen Gels" |
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10:10am-10:30am |
Break |
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10:30am-12:30pm |
Session 5: Novel Approaches for Embryonic Stem Cell Growth and Differentiation |
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10:30am-11:10am |
Invited Speaker: Mick Bhatia, McMaster University, "Controlling Human Embryonic Stem Cells by Niche Regulation" |
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11:10am-11:30am |
Emmanuel E. Baetge, Novocell, Inc., "Engineering Embryonic Stem Cells to Create a Cell Therapy for Diabetes" |
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11:30am-11:50am |
Clark K. Colton, Massachusetts Institute of Technology, "Differentiation of Murine Embryonic Stem Cells to Cardiomyocytes Is Increased Under Reduced Oxygen" |
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11:50am-12:10pm |
Jennifer Blundo, Stanford University, "Molecular Imaging of Cardiac Constructs Derived from Human Embryonic Stem Cells" |
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12:10pm-12:30pm |
Shelly Sakiyama-Elbert, Washington University, "The Effect of Controlled Growth Factor Delivery on Embryonic Stem Cell Differentiation inside of Fibrin Scaffolds" |
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12:30pm-2:00pm |
Lunch |
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2:00pm-4:10pm |
Session 6: Novel Approaches for Adult Stem Cell Growth and Differentiation |
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2:00pm-2:40pm |
Invited Speaker: Fred Gage, Salk Institute, "Neurogenesis in the Adult Mammilian Brain" |
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2:40pm-3:00pm |
Pin Wang, University of Southern California, "Engineering Stromal Cells for Supportive Differentiation of TCR-Transduced Hematopoietic Stem Cells into CD4 T Cells in Vitro" |
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3:00pm-3:20pm |
Irina Conboy, University of California, Berkeley, "Understanding Bio-Chemical Changes in the Aged Muscle Niche" |
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3:20pm-3:40pm |
Kartik Subramanian, University of Minnesota, "Directed Differentiation of Multipotent Adult Progenitor Cells into the Cells of the Hepatic Lineage" |
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3:30pm-3:50pm |
C. Lobato da Silva, Instituto Superior Técnico, Portugal, "Maximization of the Ex-Vivo Expansion of Human Hematopoietic Stem/Progenitor Cells by Direct Contact Culture with Mesenchymal Stem Cells" |
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3:50pm-5:30pm |
Poster Session with Refreshments |
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5:30pm-9:00pm |
Dinner |
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Wednesday, January 23 |
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7:00am-8:30am |
Breakfast |
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8:30am-10:30am |
Session 7: Biomaterials for Stem Cell Growth and Differentiation |
| Invited Speaker: Dennis Discher, University of Pennsylvania, "Matrix Elasticity Directs Stem Cell Lineage Specification" | |
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9:10am-9:30am |
Kevin Healy, University of California, Berkeley, "Biomimetic Materials to Control Human Embryonic Stem Cell Self-Renewal and Fate Determination" |
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9:30am-9:50am |
Sean P. Palecek, University of Wisconsin - Madison, "3D Microwell Array Culture of Human Embryonic Stem Cells Reveals Effects of Colony Morphology on Cell Growth and Differentiation" |
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9:50am-10:10am |
Todd McDevitt, Georgia Institute of Technology / Emory University, "Microparticle Delivery of Morphogenic Factors within Embryoid Bodies for Directed Embryonic Stem Cell Differentiation" |
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10:10am-10:30am |
David Brafman, University of California, San Diego, "Arrayed Cellular Microenvironments for Exploring Cell Fate" |
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10:30am-10:50am |
Break |
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10:50am-12:30pm |
Session 8: Bioreactors and Bioprocesses for Cell Expansion and Differentiation |
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10:50am-11:30am |
Invited Speaker: Ramkumar Mandalam, Cellerant Therapeutics, "Novel Universal Cell-Based Drug from Adult Hematopietic Stem Cell" |
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11:30am-11:50am |
Matt Croughan, Keck Graduate Institute, "Manufacturing Stem Cells: Lessons Learned from 15 Years of CHO Cell Culture for Recombinant Protein Production" |
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11:50am-12:10pm |
Behnam A. Baghbaderani, University of Calgery, "Large-Scale Production of Human Neural Precursor Cells in Computer-Controlled Suspension Bioreactors and Applications to the Treatment of Neuropathic Pain" |
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12:10pm-12:30pm |
Rosario Scott, Merck, "A Platform for Predictive Bioprocessing of Autologous Cells for Therapy Based on Automated Microwell Cultures" |
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12:30pm-2:00pm |
Lunch |
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2:00pm-4:40pm |
Session 9: Biomterial Scaffolds for Stem Cell Therapeutic Applications |
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2:00pm-2:40pm |
Invited Speaker: Jennifer Ellisseff, Johns Hopkins University, "Adult and Embryonic Stem Cells in Musculoskeletal Tissue Repair" |
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2:40pm-3:00pm |
Song Li, University of California, Berkeley, "Nanofibrous Scaffolds and Mesenchymal Stem Cells for Vascular Regeneration" |
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3:00pm-3:20pm |
Michael Sacks, University of Pittsburgh, "Tissue-to-Cellular Deformation Coupling in Cell-Microintegrated Elastomeric Scaffolds" |
| 3:20pm-3:40pm | Paul Critser, Indiana University School of Medicine, "Engineered Three-Dimensional Collagen-Based Extracellular Matrices Provide Microenvironmental Guidance of Endothelieal Colony Forming Cell Proliferation Potential and Vascular Network Formation in Vitro" |
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3:40pm-4:00pm |
Sherry L. Voytik-Harbin, Purdue University, "Fibril Microstructure-Mechanical Design Features of Engineered 3D Collagen-Based Extracellular Matrices Modulate Mesenchymal Stem Cell Proliferation and Lineage Specific Differentiation" |
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4:00pm-4:15pm |
Closing Remarks by David Schaffer, Conference Chair |
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