Program
Preliminary Program for SBE's 2nd International Conference |
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Date and Time |
Speakers |
Title |
Speaker Type |
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Sunday, January 18 |
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6:00PM-7:00PM |
Poster Session and Reception |
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7:00PM-10:00PM |
Dinner |
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Welcome by Ryan Gill (University of Colorado) and Sachdev Sidhu (University of Toronto) |
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Peter Schulz (The Scripps Institute) |
An Expanding Genetic Code |
Keynote |
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Monday, January 19 |
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Session 1: Protein Engineering and Evolution |
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8:15AM-8:50AM |
Frances Arnold (California Institute of Technology) |
Engineering by Evolution |
Invited |
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8:50AM-9:10AM |
Ichiro Matsumura (Emory University) |
Acinetobacter Baylyi Sp. ADP1 as a Vehicle for Gene and Genome Evolution |
Contributed |
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9:10AM-9:30AM |
Eric Shusta (University of Wisconsin, Madison) |
Engineered GFP-Based Biosensors Endowed with Nanomolar Binding Capability |
Contributed |
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9:30AM-9:50AM |
Karl Griswold (Dartmouth University) |
New Designs for Enzymatic Antimicrobial Therapies |
Contributed |
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9:50AM-10:10AM |
Scott Banta (Columbia University) |
Enzymatic and Bioactive Hydrogels from Proteinaceous Bifunctional Building Blocks |
Contributed |
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10:10AM-10:45AM |
Andreas Plückthun (University of Zürich) |
The Taming of the Shrew: Improving GPCR Expression and Stability |
Invited |
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10:45AM-11:05AM |
Break |
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Session 2: Computationally Guided Protein Engineering |
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11:05AM-11:40AM |
Gideon Schreiber (Weizmann Institute of Science) |
Computer-Based Design for Affinity and Specificity of Protein-Protein Interactions |
Invited |
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11:40AM-12:00PM |
Jesús Zurdo (Lonza Biologics) |
In Silico Aggregation Screening and Protein Engineering to Improve Developability and Safety Profiles of Therapeutic Proteins |
Contributed |
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12:00PM-12:20PM |
Monica Berrondo (Johns Hopkins University) |
Computational Predictions of the Enzymatic Activity of Single Deletion Mutants |
Contributed |
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12:20PM-12:40PM |
Feng Ding (University of North Carolina at Chapel Hill) |
Applications of Conformational and Sequence Sampling in Protein Engineering — Discrete Molecular Dynamics and Medusa Molecular Modeling Tools |
Contributed |
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12:40PM-1:15PM |
John Desjarlais (Xencor) |
Engineering Antibodies for Enhanced Effector Function, Pharmacokinetics and Low Immunogenicity |
Invited |
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1:15-2:40PM |
Lunch |
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Session 3: Biomolecular Probes and Imaging |
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2:40PM-3:15PM |
Klaus Hahn (University of North Carolina at Chapel Hill) |
New Tools to Visualize and Manipulate Signaling in Living Cells |
Invited |
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3:15PM-3:35PM |
Jennifer Cochran (Stanford University) |
Engineering Protein Ligands as Multimodal Tumor Imaging Agents |
Contributed |
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3:35PM-3:45PM |
Kevin Hoff (California Institute of Technology) |
Fluorescent Sensors for Detection of Iron Sulfur Cluster Biogenesis |
Contributed |
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3:45PM-3:55PM |
Kevin Cash (University of California, Santa Barbara) |
Electrochemical Detection of Proteins with the E-DNA Platform |
Contributed |
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3:55PM-4:15PM |
Peter Tessier (Rensselaer Polytechnic Institute) |
Analysis of Protein Misfolding and Aggregation Using Peptide Microarrays |
Contributed |
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4:15PM-4:50PM |
Stephen Michnick (University of Montreal) |
The Dark Matter of Protein Interaction Networks |
Invited |
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4:50PM-5:25PM |
Bernard Palsson (University of California, San Diego) |
Reconstruction of the Genome-Scale Human Metabolic Network Based on Build-35 and Bibliomic Data |
Invited |
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5:25PM-7:00PM |
Poster Session and Reception |
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7:00PM-10:00PM |
Dinner |
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Jay Keasling (University of California, Berkeley) |
Synthetic Biology in Pursuit of Low-Cost, Effective, Anti-Malarial Drugs |
Keynote |
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Tuesday, January 20 |
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Session 4: Engineering Pathways and Complex Phenotypes |
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8:45AM-9:20AM |
Stefan Wildt (Merck) |
Genetic and Metabolic Engineering of the Methylotrophic Yeast P. Pastoris as a Host for Therapeutic Protein Production |
Invited |
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9:20AM-9:40AM |
Stephen Van Dien (Genomatica) |
The Design, Engineering, and Evolution of Microbial Catalysts for Bio-Manufacturing of 1,4-Butanediol |
Contributed |
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9:40AM-10:00AM |
Huimin Zhao (University of Illinois at Urbana-Champaign) |
Production of Fine Chemical Phloroglucinol and Antimalarial Drug FR900098 in E. Coli |
Invited |
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10:00AM-10:20AM |
Break |
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10:20AM-10:55AM |
Sang Yup Lee (Korea Advanced Institute of Science and Technology) |
Metabolic and Cellular Engineering for the Production of Chemicals and Materials |
Invited |
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10:55AM-11:15AM |
Szu-Wen Wang (University of California, Irvine) |
Engineering Non-Native Functionality in a Caged Protein Scaffold |
Contributed |
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11:15AM-11:35AM |
John Morgan (Purdue University) |
Flux Analysis of CHO Cell Metabolism for Recombinant Protein Production |
Contributed |
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11:35AM-12:10PM |
Jon Clardy (Harvard University) |
Insect-Bacteria Mutualisms as a Discovery Engine |
Invited |
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12:10PM-2:00PM |
Lunch |
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Session 5: Synthetic Biology |
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2:00PM-2:35PM |
Steve del Cardayre (LS9) |
Renewable Petroleum ™ Products and Technologies: low cost fuel and chemical substitutes |
Invited |
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2:35PM-2:55PM |
Andreas Ernst (University of Toronto) |
Specificity Map of Synthetic Pdz-Domains |
Contributed |
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2:55PM-3:15PM |
Maung Nyan Win (California Institute of Technology) |
Programming Synthetic RNA Devices for Cellular Information Processing |
Contributed |
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3:15PM-3:35PM |
Marc Ostermeier (Johns Hopkins University) |
An Externally-Tunable Bacterial Band-Pass Filter |
Contributed |
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3:35PM-3:55PM |
Charles Gersbach (Scripps Research Institute) |
Engineered Zinc Finger Proteins for Targeted Genome Editing and Gene Regulation |
Contributed |
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3:55PM-4:15PM |
Daniel Sayut (University of Massachusetts) |
Improvement of a Minimal Genetic and Gate Using Mutant Libraries of the Luxr Transcriptional Activator |
Contributed |
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4:15PM-4:40PM |
James Liao (University of California, Los Angeles) |
Synthesis of Advanced Biofuels |
Contributed |
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4:45PM-6:30PM |
Poster Session and Reception |
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6:30PM-9:30PM |
Dinner |
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James Wells (University of California, San Francisco) |
Engineering Cells to Death |
Keynote |
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Wednesday, January 21 |
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Session 6: Molecules to Macro Systems |
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8:30AM-9:05AM |
Uwe Sauer (ETH Zurich) |
Unraveling Condition-Specific Networks of Active Metabolic Regulation |
Invited |
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9:05AM-9:25AM |
J. Christopher Love (Massachusetts Institute of Technology) |
Approaches to Profiling Immune Responses from Single-Cell Measurements |
Contributed |
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9:25AM-9:45AM |
Peng Yin (California Institute of Technology) |
Programming Biomolecular Self-Assembly Pathways |
Contributed |
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9:45AM-10:05AM |
Jamey Young (Massachusetts Institute of Technology) |
Uncovering Connections Between Metabolism and Apoptosis: a Flux Analysis Study of Hepatic Lipotoxicity |
Contributed |
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10:05AM-10:45AM |
Andrew Ellington (University of Texas, Austin) |
In Vitro Evolution of Synthetic Circuits |
Invited |
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Break |
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Session 7: Systems Biology |
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11:00AM-11:35AM |
Bruce Tidor (Massachusetts Institute of Technology) |
Molecular and Network Modeling in Synthetic and Systems Biology |
Invited |
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11:35AM-11:55AM |
Jennifer L. Reed (University of Wisconsin Madison) |
Constraint-Based Analysis of Metabolic Capacity of Salmonella Typhimurium LT2 |
Contributed |
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11:55AM-12:15PM |
Jeffrey Varner (Cornell University) |
Mathematical Modeling and Analysis of the Role of the BLR1 Protein and MAPK Activation in the Growth-Arrest and Differentiation Program of a Model Adult Stem-Cell |
Contributed |
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12:15PM-12:35PM |
Nathan Price (University of Illinois at Urbana-Champaign) |
Relative Expression Analysis for Cancer Diagnosis and Identification of Perturbed Sub-Networks |
Contributed |
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12:35PM-12:55PM |
Xuerui Yang (Michigan State University) |
Construction of Phenotype-Specific Gene Network by Synergy Analysis |
Contributed |
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Lunch |
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Session 8: Protein Engineering 2 |
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2:30PM-3:05PM |
Jim Swartz (Stanford University) |
Custom-Designed Viral Mimics as Vaccines and Delivery Vehicles |
Invited |
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3:05PM-3:25PM |
Graham Farrington (Biogen Idec Inc) |
Development and Characterization of a Novel Monovalent Antibody Platform |
Contributed |
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3:25PM-3:45PM |
Matt Delisa (Cornell University) |
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3:45PM-4:05PM |
Patrick Cirino (Pennsylvania State University) |
Design and Analysis of AraC Regulatory Protein Mutants with Altered Effector Specificity |
Contributed |
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4:05PM-4:40PM |
George Georgiou (University of Texas, Austin) |
Engineering and Preclinical Development of Human Enzymes for Cancer Therapy |
Contributed |
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