Stem cell engineering is rapidly emerging as a distinct field at the intersection of stem cell biology, regenerative medicine, and tissue engineering. Controlling stem cell fate and differentiation by balancing extracellular and intracellular approaches is leading to the development of novel platforms to probe extrinsic and intrinsic regulation of stem cell behaviors.
As stem cell therapies mature, enhanced delivery and imaging strategies to track stem cell fate and function in vivo are increasingly important as well as establishment of the necessary bioprocessing strategies to produce stem cells for clinical applications and in vitro screening platforms.
- Todd McDevitt, Georgia Institute of Technology
- Ron McKay, Lieber Institute for Brain Development
- Extracellular Programming & Reprogramming
- Intracellular Programming & Reprogramming
- Stem Cell Tissue Engineering & Morphogenesis
- Microtechnologies & High Throughput Screening
- Computational Stem Cell Biology
- Bioprocessing and Biomanufacturing Strategies
- Regenerative Therapies
Linda G. Griffith, PhD, is the School of Engineering Teaching Innovation Professor of Biological and Mechanical Engineering at MIT, where she directs the Center for Gynepathology Research and “Bio-Mimetics”, a DARPA/NIH-funded Microphysiological Systems Progra. Dr. Griffith received a Bachelor's Degree from Georgia Tech and a PhD degree from the University of California at Berkeley, both in chemical engineering. Dr. Griffith’s research is in the field of regenerative medicine and tissue engineering. Her laboratory, in collaboration with J. Upton and C. Vacanti, was the...Read more
Dr Philippe Menasché obtained his MD and PhD degrees from the University of Paris. He is currently Professor of Thoracic and Cardiovascular Surgery at the University of Paris Descartes, Chief of the Heart Failure Surgery Unit of the Hôpital Européen Georges Pompidou and Director of an INSERM (National Institute of Health and Medical Research) laboratory devoted to cell therapy of cardiovascular diseases. He started to work in this area more than 15 years ago and performed in 2000 the first human intramyocardial transplantation of autologous skeletal myoblasts in a patient with severe heart...Read more
Sean Palecek started the lab in Fall 2000, after serving as a post-doctoral researcher with Stephen Kron at the University of Chicago. Sean graduated from from the University of Delaware, majoring in chemical engineering with a minor in biology.
He began graduate studies at the University of Illinois at Urbana-Champaign, working with Doug Lauffenburger in the Department of Chemical Engineering and Alan Horwitz in the Department of Cell and Structural Biology. Sean moved with Lauffenburger moved to the Massachusetts Institute of Tech-nology, continuing his collaboration with Horwitz,...Read more
Dr. Deepak Srivastava is the Younger Family Director and a Senior Investigator at the Gladstone Institute of Cardiovascular Disease and Director of the Roddenberry Stem Cell Center at Gladstone. At the University of California, San Francisco (UCSF), Dr. Srivastava is also a Professor in the Departments of Pediatrics, and Biochemistry & Biophysics, and is the Wilma and Adeline Pirag Distinguished Professor in Pediatric Developmental Cardiology.
Dr. Srivastava’s laboratory revealed how cardiac chamber-specific gene networks are established at the transcriptional level and are...Read more