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CEP: October 2007

Before working on the Society for Biological Engineers' (SBE) Special Section titled "From Chinese Hamsters to Therapeutic Proteins"(pp. 33-52), I thought of hamsters more as pets than as life-saving animals...

Recombinant Protein Therapeutics from CHO Cells -- 20 Years and Counting

October
2007
SBE Special Section
Karthik P. Jayapal, Katie F Wlaschin, Wei-Shou Hu and Miranda G. S. Yap , Wei shou Hu
The CHO cell is at its height of technological prominence thanks to its adaptability to various culture conditions and plasticity in the context of genetic alterations. With further research, the application ofCell Culture Strategies based on...

Deciphering the Mechanisms of Therapeutic Protein Production

October
2007
SBE Special Section
Christoph L. Bausch, Daniel W. Allison, Kevin J. Kayser, Matthew V. Caple, Trissa Borgschulte
Demand for therapeutic recombinant proteins will eventually exceed current production capabilities. This is a major driver in further understanding Chinese Hamster Ovary (CHO) cell biology, which is the cell line of choice for producing these...

Industry and SBE News

October
2007
SBE Special Section
Dr. George Georgiou to Receive SBE's James E. Bailey Award; Averting an Epidemic— Novel Device Detects Avian Flu Virus in Less than Half an Hour; Cell-Free Protein Sythesis Comes of Age; Genetically Engineering Microorganisms into Pharmaceutical...

Singapore: An Emerging Leader in Biomedical Sciences

October
2007
SBE Special Section
Miranda G. S. Yap, Niki S. C. Wong
With a heavy investment in biomedical research— particularly the $330 million to build Biopolis in 2003— Singapore is seeing the fruits of its labor blossom.

Understand the Emerging Issue of Vapor Intrusion

October
2007
Environmental Management
Matthew Traister
The migration of vapors from contaminated groundwater and soil into aboveground buildings can adversely affect indoor air quality by creating an exposure pathway that may not have been addressed previously.

Avoid Problems in Process Water Systems

October
2007
Heat Transfer
Marilyn W. Blaschke, Roger D. Metzler
Prevent corrosion, emulsification and fouling by implementing these operational and chemical measures.
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