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  1. Genomatica: 15 Year Journey (and counting) - How to Derive the Most Economic Value from Metabolic Engineering

    ChemE On Demand Presentation (Metabolic Engineering Conference, 2014)

    As a founder and CEO, Christophe Schilling has led Genomatica from a developer of metabolic engineering tools to a position of leadership in biotech processes for the production of major chemicals – with multiple customers, $125 million in equity investments, and numerous awards for their...

  2. Development of a Commercially Viable Algae Biofuels Process


    This presentation will provide an overview of a process to produce algae bio-crude from algae grown in open ponds using non-potable water and non-arable soil.

  3. From Biochemical Engineering to Synthetic Biology: A Short History of Engineering Impacts on Biotechnology


    This webinar will focus on how biochemical engineering developed in response to the need for large-scale production of antibiotics in the 1940s and 50s, even though fermentation provided a route to many industrial organic chemicals prior to their production from petroleum.

  4. Electrofuel Production Using Ammonia or Iron in Reverse Microbial Fuel Cells


    The production of electrofuels requires the efficient transport of electrons from an electrochemical system into a biological system. We have approached this challenge by identifying natural chemical mediators that can be easily reduced electrochemically and are natural substrates for different...

  5. Microbial-Electrocatalytic Biofuel Production


    Dr Singer and his lab are developing an integrated Microbial-ElectroCatalytic (MEC) system to produce advanced biofuels from H2/CO2. We have engineered Ralstonia eutropha, an aerobic chemolithoautotroph, to produce biofuel products by manipulating the polyhydroxybutyrate, fatty acid and isoprenoid...

  6. Engineering Single-Cell Bioanalytics for Discovery and Bioprocess Characterization


    Discovery of new antibodies for therapeutics requires discerning tools to identify rare cells producing specific antibodies among many similar ones. Bioprocess development also relies on methods to identify optimized cell lines producing heterologous proteins. This talk will describe an approach...

  7. Viral Contamination of Biologics Manufacture—Occurrence and Mitigation


    Learn about viral contamination events and risk mitigation strategies that may be used to reduce the potential for contamination.

  8. From Biomass to Biofuels: Breaking the Cellulose Barrier


    Cellulases are of considerable current interest for converting the cellulosic content of biomass to fermentable sugars for biofuels production. To facilitate the enzymatic conversion of biomass to sugars, pre-treatment processes at high temperatures, low pH, and even in ionic liquids are candidates...

  9. Tumor Targeting Theory: Physiological Limits from Scaling Analyses, and Design Principles for Better Magic Bullets


    For the past two decades the capability of protein engineers to devise clever tumor-targeting molecules has outstripped our understanding of how these agents distribute through the body and permeate through tumors. Classical chemical engineering reaction/diffusion analyses help illustrate the...

  10. Microengineered Hydrogels for Stem Cell Bioengineering and Tissue Regeneration


    Micro- and nanoscale technologies are emerging as powerful tools for controlling the interaction between cells and their surroundings for biological studies, tissue engineering, and cell-based screening. In addition, hydrogel biomaterials have been increasingly used in various tissue engineering...