Computational Fluid Dynamics Simulation of a Quadupole Magnetic Sorter Flow Channel

North American Mixing Forum
2009 AIChE Annual Meeting
AIChE Annual Meeting
November 9, 2009 - 7:00pm
Isolation of the pancreatic islets is the important step in preparing islets for the transplantation in type 1 diabetes patients. Quadrupole magnetic flow sorting (QMS), effective in the separation of suspensions of single cells, is being modified for isolation of pancreatic islets. The separating mechanism in QMS is created by the magnetic field strength and gradient induced by a modified Halbach quadrupole magnet assembly and applied to an annular channel of separands flowing through the magnet bore. Thus, islets are subjected to vertical parallel annular flows, horizontal magnetic force, vertical sedimentation and flow through inlet and outlet spreaders and splitters as well as through peristaltic pumps. Computational fluid dynamics (CFD) models were used to simulate the islet separation in the flow channel and flow distributors in the QMS channel. Analyses of particle trajectories, splitter geometries and transport lamina were performed. The CFD results provided an adequate match with the experimental data.

Keywords: magnetic flow sorter, pancreatic islets, computational fluid dynamics, pulsatile flow&'
Professional Development Hours
0.4 PDHs
You will be able to download and print a certificate for these PDH credits once the content has been viewed. If you have already viewed this content, please click here to login.

Would you like to access this content?

No problem. You just have to complete the following steps.

You have completed 0 of 2 steps.

  1. Log in

    You must be logged in to view this content. Log in now.

  2. Purchase Technical Presentation

    You must purchase this technical presentation using one of the options below.
    If you already purchased this content recently, please click here to refresh the system's record of ownerships.


Credits 0.5 Use credits
List Price $25.00 Buy now
AIChE Members $15.00 Buy now
AIChE Undergraduate Student Members Free Free access
AIChE Graduate Student Members Free Free access
Related Topics: