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Conference Presentations - 2012 AIChE Annual Meeting

Modelling of a Filter Drying Process

Oct 29, 2012
Mark A. Pinto
Filter drying, also referred to as vacuum contact drying, is a process widely used in the pharmaceutical industry to remove water or organic solvents. The advantage of this process over other drying operations is that it can be used to dry solids that are sensitive to oxygen and temperature. The...

Exceptional Event Managemnt Applied to Continuous Pharmaceutical Manufacturing

Oct 29, 2012
Anshu Gupta
One of the important challenges in effective real time process management is the implementation of intelligent systems that can assist human operators in making supervisory control decisions, instead of simply sounding an alarm when process variables go out of range. Operator failures to exercise...

On the Selection of Ionic Liquids for the Conversion of Cellulosic Biomass Feedstock

Oct 29, 2012
Sameer Parvathikar
The use of ionic liquids (ILs) as solvents represents a promising route for the conversion of cellulosic biomass feedstock. 1,3-dialkylimidazolium ILs in particular, have become a popular and thoroughly-studied reaction media for this. Reactions such as the dissolution and hydrolysis of cellulose,...

Random Thoughts: Inspired by Rich Felder

Oct 29, 2012
Kenny Felder, Lisa G. Bullard, Rebecca Brent
This talk is part of the invited session 'Random Thoughts: Inspired by Rich Felder'. Description: This session honors Dr. Richard M. Felder, Hoechst Celanese Professor Emeritus of Chemical Engineering at North Carolina State University. Rich has been recognized for his sustained contributions to...

A Model-Based Approach for the Construction of Design Spaces in Quality-by-Design

Oct 29, 2012
Richard D. Braatz
This presentation considers the characterization of the set of allowable real parameter uncertainties for the output of a nonlinear system to be located in a prespecified target range. This word “parameter” is used by FDA and in this presentation to refer to any variable held at a fixed value...

A Shell-and-Tube Direct Steam Generator for Concentrated Solar Power Generation

Oct 29, 2012
Theodore Wiesner
?Making Solar Energy Economical? is one of the Grand Challenges posed by the National Academy of Engineering. However, innovation in concentrating solar power technologies (CSP) lags by considerable margins that of all other renewable energy technologies. The levelized cost of electricity (LCOE)...

Scientific Validation of THz Spectroscopic Measurement and Its Pharmaceutical Process Analytical Technology (PAT) Applications: Case Studies of First Principles Modeling Approach

Oct 29, 2012
Huiquan Wu
As an emerging technology, THz spectroscopy has gained increasing attention in the pharmaceutical area during the last decade. This attention is due to the fact that (1) it provides a promising alternative approach for in-depth understanding of both intermolecular interaction among pharmaceutical...

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