Conference Presentations - 2010 AIChE Annual Meeting

Multiscale Modeling and Analysis of TRPV1 Regulation in Sensory Neurons

Nov 8, 2010
Jeffrey D. Varner
TRPV1 (transient receptor potential vanilloid subtype 1) receptors play a central role in nociception and inflammatory pain. Interestingly, both agonists and antagonists of TRPV1 have been tested therapeutically, suggesting that the regulation of TRPV1 activity is a complex balance between pro- and...

Genomic Approaches to Evolutionary History of Primate Cytochromes c

Nov 8, 2010
Lawrence I. Grossman
Cytochrome c (cyt c) is a highly conserved protein among eukaryotes, mainly owing to its pivotal role in two crucial cellular processes: apoptosis and respiratory chain function. Despite its overall stability, previous studies have reported on the human lineage: (i) a high amino acid evolution rate...

High Absorption Performance of HCl in 1-Octyl-3-Methylimidazolium Chloride

Nov 8, 2010
Suojiang Zhang
Incineration of wastes and combustion of chlorine-rich coal are the major sources of local and global environmental pollution related to hydrogen chloride (HCl) emission. At the same time, HCl is a common tail gas in chemical industry such as PVC and Freon production. HCl is regarded as the most...

Multi-Scale Agent-Based Modeling of Human Endotoxemia

Nov 8, 2010
Tung T. Nguyen
The systemic inflammatory response syndrome (SIRS) often accompanies critical illness but is evoked by many stimuli e.g. infection, trauma, invasive surgery and biological stressors in general [1]. It often progresses to severe cases of sepsis with a substantial morbidity and mortality where...

A System Approach to Astrocytoma Progression

Nov 8, 2010
Chunjing Wang
Astrocytomas are brain cancers that account for 75% of neuroepithelial tumors. Accurate diagnosis is required for adequate treatment and assessing prognosis for patients. We used both gene-based and network-based approaches to find the key processes involved in astrocytoma progression from...

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