Conference Presentations - 2010 AIChE Annual Meeting

S-PEEK has been known as one of the promising candidates for fuel cell application since it has high thermo-oxidative stability and extraordinary mechanical properties as well as high cost effectiveness. However, the nanoscale structure and transport properties for S-PEEK have not been thoroughly...

There is a multitude of possible formulation pathways for pharmaceutical compounds among which polymorph, solvate, salt and cocrystal formation are the most common. Finding the optimal formulation by experimentation alone is often expensive and time consuming. In a quality by design environment,...

Lung diseases include some of the most widespread and deadly conditions known to affect people in the US today. One of the main challenges in treating lung disease is the difficulty of diagnosis. Clinical diagnosis remains largely dependent upon symptomatic-based diagnoses; many cases can be either...

Quality by Design is a technical exercise that should be performed upstream in the design of the production train for a given product. Although each processing step will have its own inputs and outputs that effect product quality, it is clear that raw materials properties are important for the...

The objective of this study was to understand the impact of API particle size on various blend and tablet quality attributes of a sustained release oral tablet formulation produced via a direct compression process. The API primary particle size and agglomerate size were identified as critical...

Throughout its history, Genentech scientists and engineers pioneered and then exploited the use of recombinant DNA technology to develop and manufacture proteins and monoclonal antibodies for therapeutic use. Today an entire industry uses these genetic engineering techniques in pursuit of novel...