2012

New Challenges and Opportunities for Pharmaceutical Manufacturing Science

Oct 29, 2012
Vincent Vilker
New Challenges and Opportunities for Pharmaceutical Manufacturing Science Vincent L Vilker and Mansoor A Khan, CDER/FDA The increasing sophistication of modern drug products is leading to unprecedented challenges and opportunities for pharmaceutical manufacturing. At the same time, scientific and...

The Mixed Matrix Membrane Story

Oct 29, 2012
Santi Kulprathipanja
The talk will highlight the evolution of Mixed Matrix Membranes (MMM), developed in the mid-1980s. The talk will first provide an introduction into the strategic thinking that led to the development of the water stable adsorbent ADS-200. ADS-200 is a cellulose acetate bound zeolite used in the...

Optimal Plant Operation of Industrial Reverse Osmosis Desalination

Oct 29, 2012
Mingheng Li
A comprehensive first-principles based mathematical model, which explicitly accounts for membrane hydraulic permeability, pump characteristic curves and retentate pressure drop, is developed to describe the reverse osmosis desalination process. Parameters used in the model are derived from data...

Metal-Organic Framework (MOF) Materials and Membranes for Molecular Separations

Oct 29, 2012
Sankar Nair
This talk will describe our recent progress in the synthesis and processing of MOF/ZIF materials for molecular separation applications, and their subsequent use in the fabrication of membrane/thin film devices for such uses. New separations technology is key to increased energy efficiency in the...

Looking to the Future in Continuous Pharmaceutical Manufacturing

Oct 29, 2012
Richard D. Braatz
This presentation describes the motivations, challenges, and opportunities in continuous pharmaceutical manufacturing. Some of the motivations are particularly intriguing, such as semicontinuous and continuous-flow unit operations that have the potential to have order-of-magnitude higher...

Designing LNG Vapor Dispersion Exclusion Zones to Protect the Public

Apr 5, 2012
Jerry Havens
The LNG industry, if not the entire energy industry, may be at a crossroad. Expectation of large shale gas supplies in the United States, with a backdrop of international economies in precarious states, makes more uncertain the promise of major investments in LNG import facilities. Already, a...

Major Turnaround in An Olefins Plant: A Process Safety Point of View

Apr 4, 2012
Pablo Ricardo Barrera
The process safety management in an industrial plant is a critical success factor for companies integrated in a global market. The equipments should have maximized performance and operational runlenght without compromising process safety. The challenge for excellence performance drives companies to...

Modeling of Underground Hydrogen Pipelines

Apr 4, 2012
Elizabeth Lutostansky
Hydrogen is a critical component in the production of cleaner fuels. Underground pipelines provide a safe, reliable supply of hydrogen to refineries and the petroleum industry. Proper assessment of the risks associated with underground hydrogen pipelines requires an accurate model of the jet fire...

Hydrocarbons Turnarounds EHS Readiness

Apr 4, 2012
Jon Pucheu
The Dow Hydrocarbons Business has a thorough process for managing excellent EHS performance during Turnarounds. We name an EHS Focal Point for each Turnaround 2 years in advance. A Turnaround EHS Preparation and Execution plan is developed and followed. An EHS Readiness Assessment is conducted with...

Two Incompetent Workers; Too Close for Comfort ñ Part 1

Apr 4, 2012
Mike Broadribb
Learning from experience is one of the four pillars of Risk-Based Process Safety. Incidents that occur at one facility often provide opportunities to strengthen management systems at other facilities. Sharing the technical lessons learned from incidents is morally right and vital to improving...

Using LOPA to Establish SILs for Power Outage Protection

Apr 4, 2012
Carlos A. Barrera
Catastrophic incident root causes often may be correlated with power outages. An unanticipated power outage may be an initiating event that leads to a process upset or even an emergency shutdown of a process unit. If the planning and implementation of the emergency shutdown are managed incorrectly...

Emergency Block Valves

Apr 4, 2012
Joe Viviano
An Emergency Block Valves (EBV) is used as a means of isolating flammable or toxic substances in the event of a leak or fire. The installation, and use, of EBV's in many hydrocarbon services will significantly reduce the potential of fire and explosion damages caused by loss of hydrocarbon...

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