2009

Diurnal Cycling of Triacylglycerides in a Chlorophyte Sp.: Implications for the Production of Algal Biofuels

Nov 11, 2009

Keith Cooksey

There is no doubt that crude oil will be depleted eventually. The concept of global warming is now well accepted. Given these twin constraints, it behooves us to find alternative fuels, especially liquid ones for transportation. Microalgae have the potential to both reduce increases in greenhouse...

A QbD Approach to Selection of Materials for Drug Product Packaging and Medical Devices

Nov 11, 2009

Arthur J. Shaw

This presentation will describe a QbD approach to the selection of materials used to package drug products or to construct medical devices that deliver drug products. Special attention is required for materials that contact drug products due to extractables and leachables (E&L) considerations...

Extremophilic Microalgae: Advanced Lipid Production for Biofuels

Nov 11, 2009

Brent Peyton

On the Optimization of the Cooling Profile in Crystallization Using the Design of Dynamic Experiments Approach

Nov 11, 2009

Christos Georgakis

To control the size and shape of crystals during batch crystallization, one must either have an accurate crystal growth and nucleation model or run a series of experiments to find the optimal operating conditions. Since the former is a very intricate and time-consuming task, especially for new...

Dynamic Model of a Solar Thermal Transport Tube Reactor for Control Purposes

Nov 11, 2009

Elizabeth Saade

A solar thermal reactor receives concentrated solar irradiation and uses this energy to thermally convert biomass into synthesis gas (H2, CO and CO2). The operation of this reactor is affected by the presence of clouds, which act as a disturbance for this process. When clouds are partially covering...

The Use of the Design of Dynamic Experiments Methodology to Quantify the Design Space in QbD Tasks

Nov 11, 2009

Christos Georgakis

The present communication describes a systematic methodology for the quantification of the Design Space characteristics of batch pharmaceutical process. The methodology is applicable to processes which are not known in great detail for a mathematical model to be available. The approach designs a...

Direct Monitoring of Oil Production in Individual Microalgae in Situ by Raman Spectroscopy

Nov 11, 2009

Huawen Wu

Microalgae, producing oils that can be converted into biodiesel, are one of the promising candidates for the next generation of viable fuel to help solve the global energy crisis. However, the recent booming of research on microalgae, so far appears not benefiting from the booming of modern high-...

Physical and Nutrient Stresses for Stimulating Algal Biofuel Production: Quantitative Control of Fermentation

Nov 11, 2009

Damian Carrieri

Microalgae and cyanobacteria are phototrophs that have important advantages over land-based crops as potential feedstocks for energy production. They do not compete with food-crops for arable land, can often be cultured in saline or brackish waters, and produce non-recalcitrant biopolymers. One...

Purification of Recombinant Plant-Made Proteins From Corn by Ultrafiltration

Nov 10, 2009

Matthew Aspelund

The use of corn as an expression host is an attractive system for the production of plant-made proteins. The use of plants lowers upstream costs making downstream the significant production cost. For some proteins, crossflow ultrafiltration could be a lower cost alternative. The potential for doing...

Inline Mixing Device for Medical Applications

Nov 10, 2009

Yves Delmotte

In the surgical field, the mixing of two combined fluid streams is required to form fibrin glue, used as a tissue sealant or a hemostat. The sealant components, fibrinogen and thrombin, have different viscosities, respectively 150 and 1 cps at 37°C. The viscosity of fibrinogen depends on the...

Electrical Characterization of Organic-Inorganic Hybrid Active Layer for Bulk Heterojunction Solar Cell

Nov 10, 2009

Chinho Park

An organic-inorganic hybrid composite of cadmium selenide (CdSe) quantum dots with conjugated polymer poly (3-hexylthiophene-2,5-diyl) (P3HT) was employed as an active layer for the bulk hetero- junction solar cell. CdSe quantum dots were synthesized by conventional hot injection method with...

Open Innovation from the Perspective of a Diversified Fortune 500 Company: Effective Management of the University-Company Interface

Nov 10, 2009

Robert R. Gruetzmacher

The title of this session is an expression of the interest on the part of companies and universities to work together to create business opportunity. Universities are becoming key sources of discovery and with recent changes in government funding (amount and process) academia will be playing an...

Gram-Scale Isolation of IEC Charge Variants Using Displacement Chromotography

Nov 10, 2009

Ryan Hutchinson

The pharmacokinetic profiles of monoclonal antibody charge variants are poorly understood because they differ only slightly from the “main” antibody species, are low in abundance, and extremely difficult to isolate in pure pools for intensive in vitro and in vivo studies. Because of this, the...

Mixing Scale-Down Studies for the Scale-Up of Beer Fermentation

Nov 10, 2009

Alvin Nienow

Beer fermentations have traditionally been undertaken without the use of mechanical agitation with mixing being provided only by the CO2 evolved during the batch process. This approach has largely been maintained because of the belief in industry that rotating agitators would damage the yeast. In...

A Microfluidic Obstacle Course for Arraying and Detection of Microbeads, Lipobeads and Liposomes

Nov 10, 2009

Shahab Shojaei-Zadeh

Bead based microarrays are promising platforms for implementing the high throughput, multiplexed assaying of the binding interactions of biomolecules (for example the binding of antigens and antibodies, or the conjugation of membrane receptors with small molecule ligands). In these arrays, each...

Assessing the Viability of Solid Sorbents for CO2 Capture From Coal-Fired Power Plants

Nov 10, 2009

Holly Krutka

Carbon capture and sequestration (CCS) can be an important component of reducing worldwide CO2 emissions from stationary point sources, such as coal-fired power plants. Aqueous amines and ammonia are being demonstrated for CO2 capture in a temperature swing cyclic process. Solid sorbents can also...

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