2008

Purifying Therapeutic Monoclonal Antibodies

May
2008
SBE Special Section
Amit Mehta, Amy Len, Benedicte Lebreton, Bradley Wolk, Jace Fogle, Martha Lovato Tse, Nuno Fontes, Robert van Reis, Roshan Shrestha
Eliminating the affinity chromatography step in the mAb purification process trims equipment requirements, shrinks the plant footprint— and reduces costs.

Use Spreadsheets to Estimate Modeling Parameters

February
2008
Computational Methods
Tomas B. Co
Dynamic process modeling based on non-uniformly sampled data and multiple sampling runs, even for nonlinear systems, can be performed using spreadsheet implementations of the weighted-least-squares (WLSQ) and Runge-Kutta WLSQ methods.

Understand Discrete Nanoscale Transport

June
2008
On The Horizon
Anh-Tuan Dinh, Chinmay Pangarkar, Samir Mitragotri
Unlike mass, energy and momentum transfer, which are described by continuum equations, the movements and interactions of the nanoscale entitites within a cell constitute the transport phenomenon known as discrete nanoscale transport (DNT).

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