2007

Singapore: An Emerging Leader in Biomedical Sciences

October
2007
SBE Special Section
Niki S. C. Wong
With a heavy investment in biomedical research— particularly the $330 million to build Biopolis in 2003— Singapore is seeing the fruits of its labor blossom.

Diagnosing Maldistribution in Towers

May
2007
Reactions and Separations
Simon X. Xu
Gamma CAT-scan technology makes possible the collection of much more vital online process information than conventional diagnostic techniques.

Assess the Performance of Positive-Displacement Pumps

December
2007
Fluids and Solids Handling
AIChE's Equipment Testing Procedures Committee
Here's how to evaluate rotary pumps— gear, lobe, vane and multiple-screw designs— regardless of whether the material being handled is a Newtonian or non-Newtonian fluid.

Computational Fluid Dynamics - Power to the People

April
2007
Computational Methods
Suzanne Shelley
Today's CFD Programs are more powerful and easier to use than ever, thanks to improved mesh-generation strategies, computational methodologies, user interfaces and enhanced graphics capabilities. Cover photo courtesy of Acusim and Intelligent Light.

Realistically Predict Capacity and Pressure Drop for Packed Columns

July
2007
Reactions and Separations
Henry Z. Kister
Generalized pressure-drop correlation (GPDC) charts have been the standard for predicting packing flood points and pressure drops. This article guides engineers on the correct and incorrect uses of the GPDC interpolation procedure, and updates the...

Apply an Integrated Approach to Catalytic Process Design

February
2007
Reactions and Separations
James Nehlsen
To ensure a practical, efficient and economically viable process, first consider how a successful catalytic reaction system would work, then focus on making a catalyst with the desired characteristics.

Fuel Cells, the Hydrogen Economy and You

November
2007
On The Horizon
Herbert W. Cooper
Chemical engineers will play an important role in the development and deployment of fuel cells. This primer summarizes some of the key technical and economic issues that must be overcome.

Selecting Elbows for Pneumatic Conveying Systems

September
2007
Fluids and Solids Handling
Paul Wagner
The right elbow can keep your system operating at peak performance, reduce maintenance costs, and minimize material attrition and elbow wear. This article describes common elbows and outlines factors to consider when selecting one.

The Rise of China - Progress at What Price?

June
2007
News Feature
Boonsri Dickinson
As China undergoes an industrial revolution, its once pristine lands are being choked by pollution from coal-fired plants. Spurred by the upcoming 2008 Olympics in Beijing, China is quickly cleaning the air. And, it has long-term plans to invest...

U.S. Research Universities - Globalize or Face Demise?

January
2007
Special Section
William R. Schowalter
Although the effects of globalization have revolutionized corporate behavior, they are only beginning to affect the thinking, and much less the policies, of U.S. research universities. It is something that should be embraced, rather than resisted.

The Road to Sustainability

June
2007
Special Section
Darlene Schuster
What are some of the resources available to support industry's implementation of sustainability?

Recombinant Protein Therapeutics from CHO Cells -- 20 Years and Counting

October
2007
SBE Special Section
Karthik P. Jayapal, Katie F Wlaschin, Wei-Shou Hu and Miranda G. S. Yap , Wei-Shou Hu
The CHO cell is at its height of technological prominence thanks to its adaptability to various culture conditions and plasticity in the context of genetic alterations. With further research, the application ofCell Culture Strategies based on...

Benchmarking Sustainability

June
2007
Special Section
Calvin Cobb, Darlene Schuster, Beth Beloff and Dicksen Tanzil , Darlene Schuster
Unlike other sustainability indices, the AIChE Sustainability Index (SI) accounts for key factors that are fundamental to the chemical process industries.

Keeping the Competitive Edge

June
2007
Special Section
Lise Laurin
Applying the total cost assessment (TCA) methodology, which accounts for intangibles, provides a more complete evaluation of costs and benefits with the risks associated with them.

Create Business Value Through Process Modeling

September
2007
Management
Bernard McGarvey
As businesses strive to improve productivity, process modeling can be a powerful tool. This article explores the role of modeling in enhancing the effectiveness and efficiency of process development and manufacturing.

Don't Let History Repeat Itself

August
2007
Safety
John F. Murphy, P.E.
Heed these lessons learned from investigations conducted by the Chemical Safety and Hazard Investigation Board to prevent accidents at your site.

High-Shear Mixers: Still Widely Misunderstood

November
2007
News Feature
Suzanne Shelley
Advanced modeling techniques and improved geometric features are helping designers and users of rotor-stator mixers to demystify these complex devices, and get more consistent predictable results.

Use LOPA to Determine Protective System Requirements

February
2007
Safety
W. Kent Goddard
This article explains how to use layers of protection analysis (LOPA) to evaluate various process safeguards, determine if safety instrumented functions are required, and establish what safety integrity levels are needed to reduce risks to tolerable...

Designing Multiple-Diameter Relief Piping

July
2007
Safety
John Garvin
Most design methods consider a single pipe diameter. Here's how to evaluate multiple-diameter systems and to calculate conservative single-pipe representations.

Nanotechnology: Cause for Concern?

September
2007
News Feature
Kristine Chin
Nanotechnology— it's a small science with big stakes. Some of the unique properties that make nanoscale materials useful may also pose hazards to humans and the environment. Can the EPA find a way to effectively regulate these tiny high-tech...

A Renewable Route to Propylene Glycol

August
2007
News Feature
Suzanne Shelley
Rapid expansion in biodiesel production has spurred a bumper crop of competing processes to turn byproduct glycerin into propylene glycol.

The G-Value for Agitator Design: Time to Retire It?

March
2007
Fluids and Solids Handling
Gregory T. Benz
This commonly used number does not correctly address the influence of viscosity, and has no relationship to performance parameters such as fluid velocity and blend time. This article recommends actual measures of agitator performance that should be...

Deciphering the Mechanisms of Therapeutic Protein Production

October
2007
SBE Special Section
Daniel W. Allison
Demand for therapeutic recombinant proteins will eventually exceed current production capabilities. This is a major driver in further understanding Chinese Hamster Ovary (CHO) cell biology, which is the cell line of choice for producing these...

Controlling Emissions During Cold Furnace Startup

February
2007
Environmental Management
Charles E. Baukal Jr.
High carbon monoxide emissions from a furnace while its temperature is being ramped up can exceed permit limits if appropriate measures are not taken. Here are a few suggestions.

Improve Catalytic Oxidizer Operation

January
2007
Environmental Management
John C. Bonacci
A catalyst guard bed is a simple, low-cost modification that reduces catalyst-replacement costs, saves natural gas and cuts energy expenses.

Avoid Common Pitfalls When Using Henry's Law

September
2007
Environmental Management
Francis L. Smith
Here is practical guidance on the use of Henry's law in engineering calculations and how to account for the temperature dependence of the Henry's constant— which is often ignored but which can be crucial for accurate process design.

Selecting Nickel Alloys for Corrosive Applications

May
2007
Materials
Paul Crook
Nickel and its alloys offer resistance to attack by a wide range of chemicals, including acids, alkalis and salts, making these materials suitable for may CPI applications.

Streamlining the Validation Process

March
2007
Management
Tim Flanigan
Today, validation is no longer an afterthought for the design and construction of a new or renovated process or facility. It is, in fact, recognized as an integral part of the total project. Fully integrated services are now available to ensure a...

Predesign for Pollution Prevention and Control

June
2007
Environmental Management
Gael D. Ulrich
A plant's intrinsic cleanliness is determined during the predesign stage. This article provides guidance for making critical decisions during preliminary design.
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