2006

CEP: Update

May
2006
News Update
Bioprocessing Systems Go disposable: Single-use disposable technology is gaining acceptance in the bio-pharmaceutical arena, especially with processors seeking to reduce their operating costs and add flexibility to their manufacturing schemes...

Prevent Pulsation Problems in Piping Systems

March
2006
Fluids and Solids Handling
Mark Corbo
Eliminate unnecessary damage in piping systems by following these guidelines to avoid pulsations from pumps and compressors.

Applying the Paradigm Case Method for Flowmeter Selection

September
2006
Fluids and Solids Handling
Jesse Yoder
This effective approach to flowmeter selection involves a step-by-step method that begins by matching the application with the flowmeter(s). Then, a series of criteria are applied to narrow the selection.

Improve Safety by Improving Human Performance

August
2006
Safety
Donald K. Lorenzo
Follow these guidelines to identify situations in which human errors are likely to occur and to correct potential problems early enough to avoid adverse consequences.

Understanding Crystallization and Crystallizers

October
2006
Fluids and Solids Handling
Ketan D. Samant, Lionel O'Young
Gain qualitative insight into the basic mechanisms of crystallization, the principles of crystallizer operation, and the ways in which these concepts relate to the selection and application of the various crystallizer configurations in industrial...

Designing Pneumatic Conveying Systems

May
2006
Fluids and Solids Handling
Eric Maynard
Use this 9-step methodology to design and operate a reliable and cost-effective system to efficiently transport materials.

Cost Management in Heat-Transfer-Fluid Systems

July
2006
Heat Transfer
Conrad E. Gamble, P.E.
By taking ownership of fluid-related decisions for the entire life of the project, from design through dismantling, users can secure the best and lowest-cost approach in process heating and cooling.

Addressing Energy Supply Vulnerabilities

April
2006
Critical Issues
Herbert W. Cooper
Can a mega-worldwide energy interruption occur? The perfect storm may be brewing with such events as natural disasters, acts of terrorism and international disputes. This article explains how your company can prepare to effectively handle an energy...

Troubleshooting Distillation Simulation

June
2006
Reactions and Separations
Stanislaw K. Wasylkiewicz
A tool called azeotrope pressure sensitivity analysis (APSA) can shed light on the dependence of an azeotrope's composition and temperature on changes in pressure.

Designing Suspension-Mixing Systems

January
2006
Fluids and Solids Handling
Frantisek Rieger, Pavel Ditl
Impeller and vessel geometries are key factors in selecting mixing equipment to efficiently suspend particulate solids in slurries

Developing Safety Standard for Pilot Plants

October
2006
Safety
Richard P. Palluzi
Safety standards can significantly improve pilot plant safety and increase efficiency. This article addresses many of the issues involved in developing, deploying and using such standards.

Applications in Drug Delivery and Tissue Engineering

February
2006
SBE Special Section
Ali Khademosseini, Robert Langer
Nanotechnology is an emerging field that could potentially make a major impact on human health. Nanomaterials promise to revolutionize medicine and are increasingly used in drug delivery or tissue engineering applications.

Graphically Assess a Reactor's Characteristics

March
2006
Reactions and Separations
David Glasser, David Milne, David Glasser, Diane Hildebrandt and Brendon Hausberger
Use this technique to analyze reactor/reaction systems for which dependable kinetic data are available, or to quickly find the operating characterisitics needed for the maximum selectivity of a reactant.

Rapid Process Design

September
2006
Reactions and Separations
Michael Doherty, Sagar B. Gadewar
Use this structured approach, which combines preliminary experimental data with predictive methods and heuristics, to quickly generate and screen process alternatives at the early stages of a new venture.

Designing Resilient Engineered Systems

April
2006
Safety
Susan M. Mitchell
By viewing resiliency as a property of complex systems, it may be possible to develop resilient systems that can withstand unanticipated failures without disastrous consequences.

Screening Reactive Chemical Hazards

May
2006
Safety
Yen-Shan Liu
Use these tools to identify potentially reactive chemical hazards and avoid the expense of conducting numerous detailed hazard assessments.

Predesign with Safety in Mind

July
2006
Safety
Gael D. Ulrich, Palligarnai T. Vasudevan
This article will help you develop strong safety instincts that will guide you in making critical decisions in the preliminary design phase.

Tackling the Human Challenges of Facility Security

February
2006
Safety
Bill Effron, Dennis A. Attwood
The increased complexity of security systems may come at the expense of the user. Thus, they must be designed to match their operators' capabilities and limitations.

Understand Temperature Change in Process Stream Mixing

September
2006
Heat Transfer
Anil K. Mehrotra, Dharmendra Tiwary
The isobaric and adiabatic mixing of process streams can yield an outlet stream temperature that is either in between, higher than, or lower than the inlet stream temperatures. This article uses simulation to explore temperature-change scenarios in...

Optimizing Batch Operations

January
2006
Reactions and Separations
Kah Loong Choong, Robin Smith
Use this novel method to optimize the operating conditions as they vary through time in batch processes.

Use Cascade Analysis to Optimize Water Networks

July
2006
Environmental Management
Dominic Chwan Yee Foo, Yin Ling Tan, Zainuddin Abdul Manan
This numerical technique for identifying fresh water and wastewater targets eliminates the tedious and time-consuming steps of graphical targeting approaches. Use it to complement the graphical techniques in the design and retrofit of water networks.

Pipeline Pressure Drop: A New Design Correlation

June
2006
Fluids and Solids Handling
Roger Gilmont
A linear equation has been derived to accurately calculate the flowrate of fluids in the laminar and turbulent regions, and to derive an equation for use in the transitional regions.

Fulfilling the Promise of Nanomedicine

February
2006
SBE Special Section
Cristina Roman Vas, Rita D'Aquino with Tim Harper
Leveraging nanotechnology in the life science industries has given scientists new tools with which they have the potential to transform the world of medicine.

Building Models from Simulator Runs

January
2006
Computational Methods
Aad van Veldhoven, Magali de Macedo
The design-of-experiments approach has the advantage of providing the framework to build complex models with minimum use of time and effort.

Designing a Facility for API Development

March
2006
Plant Design
Terrence Fay, Yasha Zelmanovich
Kilo labs are instrumental in scaling up the production of active pharmaceutical ingredients. This article discusses the critical factors that must be considered to design such a facility.

Mother Nature as both Doctor and Patient

November
2006
SBE Special Section
Edwin N. Lightfoot
Once we have grasped some essentials of this riotous, but surprisingly well ordered world, we shall find our transport phenomena background to have real utility.

Right-Sizing Environmental Controls

June
2006
Environmental Management
E. Joseph Duckett
Size does matter - and bigger is not necessarily better when it comes to pollution control. It is more important to be the right size than the largest size.
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