2006

CEP: Update

May
2006
News Update
Bioprocessing Systems Go disposable: Single-use disposable technology is gaining acceptance in the bio-pharmaceutical arena, especially with processors seeking to reduce their operating costs and add flexibility to their manufacturing schemes...

Understanding Crystallization and Crystallizers

October
2006
Fluids and Solids Handling
Ketan D. Samant, Lionel O'Young
Gain qualitative insight into the basic mechanisms of crystallization, the principles of crystallizer operation, and the ways in which these concepts relate to the selection and application of the various crystallizer configurations in industrial...

Designing Pneumatic Conveying Systems

May
2006
Fluids and Solids Handling
Eric Maynard
Use this 9-step methodology to design and operate a reliable and cost-effective system to efficiently transport materials.

Cost Management in Heat-Transfer-Fluid Systems

July
2006
Heat Transfer
Conrad E. Gamble, P.E.
By taking ownership of fluid-related decisions for the entire life of the project, from design through dismantling, users can secure the best and lowest-cost approach in process heating and cooling.

Addressing Energy Supply Vulnerabilities

April
2006
Critical Issues
Herbert W. Cooper
Can a mega-worldwide energy interruption occur? The perfect storm may be brewing with such events as natural disasters, acts of terrorism and international disputes. This article explains how your company can prepare to effectively handle an energy...

Troubleshooting Distillation Simulation

June
2006
Reactions and Separations
Stanislaw K. Wasylkiewicz
A tool called azeotrope pressure sensitivity analysis (APSA) can shed light on the dependence of an azeotrope's composition and temperature on changes in pressure.

Designing Suspension-Mixing Systems

January
2006
Fluids and Solids Handling
Frantisek Rieger, Pavel Ditl
Impeller and vessel geometries are key factors in selecting mixing equipment to efficiently suspend particulate solids in slurries

Prevent Pulsation Problems in Piping Systems

March
2006
Fluids and Solids Handling
Mark Corbo
Eliminate unnecessary damage in piping systems by following these guidelines to avoid pulsations from pumps and compressors.

Applying the Paradigm Case Method for Flowmeter Selection

September
2006
Fluids and Solids Handling
Jesse Yoder
This effective approach to flowmeter selection involves a step-by-step method that begins by matching the application with the flowmeter(s). Then, a series of criteria are applied to narrow the selection.

Improve Safety by Improving Human Performance

August
2006
Safety
Donald K. Lorenzo
Follow these guidelines to identify situations in which human errors are likely to occur and to correct potential problems early enough to avoid adverse consequences.

Developing Safety Standard for Pilot Plants

October
2006
Safety
Richard P. Palluzi
Safety standards can significantly improve pilot plant safety and increase efficiency. This article addresses many of the issues involved in developing, deploying and using such standards.

Applications in Drug Delivery and Tissue Engineering

February
2006
SBE Special Section
Ali Khademosseini, Robert Langer
Nanotechnology is an emerging field that could potentially make a major impact on human health. Nanomaterials promise to revolutionize medicine and are increasingly used in drug delivery or tissue engineering applications.

Graphically Assess a Reactor's Characteristics

March
2006
Reactions and Separations
David Glasser, David Milne, David Glasser, Diane Hildebrandt and Brendon Hausberger
Use this technique to analyze reactor/reaction systems for which dependable kinetic data are available, or to quickly find the operating characterisitics needed for the maximum selectivity of a reactant.

Rapid Process Design

September
2006
Reactions and Separations
Michael Doherty, Sagar B. Gadewar
Use this structured approach, which combines preliminary experimental data with predictive methods and heuristics, to quickly generate and screen process alternatives at the early stages of a new venture.

Screening Reactive Chemical Hazards

May
2006
Safety
Yen-Shan Liu
Use these tools to identify potentially reactive chemical hazards and avoid the expense of conducting numerous detailed hazard assessments.

Predesign with Safety in Mind

July
2006
Safety
Gael D. Ulrich, Palligarnai T. Vasudevan
This article will help you develop strong safety instincts that will guide you in making critical decisions in the preliminary design phase.

Tackling the Human Challenges of Facility Security

February
2006
Safety
Bill Effron, Dennis A. Attwood
The increased complexity of security systems may come at the expense of the user. Thus, they must be designed to match their operators' capabilities and limitations.

Designing Resilient Engineered Systems

April
2006
Safety
Susan M. Mitchell
By viewing resiliency as a property of complex systems, it may be possible to develop resilient systems that can withstand unanticipated failures without disastrous consequences.

Designing a Facility for API Development

March
2006
Plant Design
Terrence Fay, Yasha Zelmanovich
Kilo labs are instrumental in scaling up the production of active pharmaceutical ingredients. This article discusses the critical factors that must be considered to design such a facility.

Mother Nature as both Doctor and Patient

November
2006
SBE Special Section
Edwin N. Lightfoot
Once we have grasped some essentials of this riotous, but surprisingly well ordered world, we shall find our transport phenomena background to have real utility.

Right-Sizing Environmental Controls

June
2006
Environmental Management
E. Joseph Duckett
Size does matter - and bigger is not necessarily better when it comes to pollution control. It is more important to be the right size than the largest size.

Industrial-Scale Flare Testing

May
2006
Environmental Management
Charles Baukal, Jianhui Hong, Mahmoud Fleifil, Robert Schwartz
Advanced flare testing at full scale can help to ensure that the system operates as designed. This article explains what's involved and the parameters that should be measured and evaluated to demonstrate performance, reliability and safety.

Simplify Wastewater Treatment Process Design

January
2006
Environmental Management
Apostolos Vlyssides, Elli Maria Barampouti, Sofia Mai
Unlike time-consuming conventional methods, this approach to designing a dissolved air flotation (DAF) plant requires only the physical characteristics of the flocs — their size and density, flowrate and temperature.

Avoid the Pitfalls of Bioprocess Development

August
2006
Process Development
Mukesh Doble
This article presents the challenges that an engineer might encounter when designing or scaling up bioprocesses and offers practical solutions, including those cited in literature.

Who Done It? The ABCs of Environmental Forensics

March
2006
Environmental Management
Jeffrey Bolin, Matthew Schroeder, Michael Sklash
These tools and techniques can be used to make sense of soil or groundwater contamination - where it came from, who is responsible for it, and how to fairly allocate the costs to clean it up.

Bioprocess Design for a Novel Vaccine

November
2006
SBE Special Section
Barry C. Buckland
The challenges of vaccine development are not limited to identification of suitable antigens, adjuvants and delivery methods, but include regulatory, technical and manufacturing hurdles in translating a vaccine candidate to the clinic.

Fundamentals of Effective Leadership

June
2006
Career Catalyst
Richard J. Kinsley
To become a leader people want to follow, focus on the team's objectives, avoid self-deception, build strong relationships, and enable others to achieve the team's goals.

Cancer's Newest Deadly Foe

February
2006
SBE Special Section
Suzanne A. Shelley
An array of nanoscale developments are poised to revolutionize cancer diagnosis and drug discovery efforts, and create new ways to target the delivery of potent, often toxic drug therapies, while reducing their dose-limiting side effects.

Reduce Business Risk with a CMS

October
2006
Environmental Management
Robert F. Boland
A compliance management system (CMS) helps companies meet regulatory reporting requirements, improve environmental performance, reduce environmental compliance costs, and increase organizational efficiency. Here's a run-down of what to look for when...

Match the Effort to the R&D Investment

January
2006
Career Catalyst
Kelly Ibsen
Using a phased engineering approach to guide R&D projects will improve efficiency and avoid costly experimental excursions.
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