University of Pennsylvania School of Medicine- Center for Cancer Pharmacology

Tuesday, November 18, 2008
3:15PM-5:45PM • T9 • Cost $20*

Proteomics and Systems Biology Core Facility

The goal of the Proteomics and Systems Biology Core is to foster basic and clinical research through the availability of state-of-the-art 2-dimensional differential in-gel electrophoresis (2D-DIGE) and mass spectromtery (MS) technology including liquid chromatography tandem MS (LC-MS/MS).  This latter technique is used as they key technology for the quantitative and quantitative characterization of proteins. The principal approach for the analysis of proteins is ‘bottom-up’ proteomics, where all proteins are proteolytically digested, producing peptides derived from the original proteins.  Protein identifications are made using state-of-the-art database search engines together with bioinformatics expertise provided by the institute of Translational Medicine and Therapeutics.  

* Transportation will be provided to and from the Marriott.  Buses will board from the Marriott - 12th Street entrance