Vladimir Razinkov

Vladimir Razinkov

Principal Scientist
Amgen

2006-current        Amgen Inc., Seattle, WA
                              Principal Scientist, Department of Drug Product Development
Formulation and pre-formulation development. High throughput screening, candidate selection and characterization of biopharmaceuticals.
2004-2006      MedImmune Inc., Gaithersburg, MD
                        Scientist II, Department of Analytical Biochemistry                
2002-2004       Protein Solutions, Piscataway, NJ                     
                        Senior Scientist                     
1999-2002       Wyeth, Pearl River, NY
                        Scientist, Department of Biological Chemistry and Enzymology                       
1996-1999      Postdoctoral Fellow/Investigator/Instructor  
                        Department of Molecular Biophysics and Physiology, Rush Medical College, 
                        Rush-Presbyterian-St.Luke’s Medical Center, Chicago, Illinois,
         
Ph.D.     1994       Biophysics,
                             Shemyakin & Ovchinnikov Insitute of Bioorganic Chemistry and Moscow
                             Institute of Physics and Technology, Moscow, Russia  
M.S.    1991       Applied Physics and Mathematics,    
                             Moscow Institute of Physics and Technology, Moscow, Russia 

SELECTED  PUBLICATIONS

1. Banks DD, Latypov RF, Ketchem RR, Woodard J, Scavezze JL,Siska CC, Razinkov VI, Native-state solubility and transfer free energy as predictive tools for selecting excipients to include in protein formulation development studies, JOURNAL OF PHARMACEUTICAL SCIENCE 101: 2720–2732, (2012)
2. Effective charge measurements of lysozyme reveal ion-specific protein interactions to be direct, and governed by anion identity,Yatin R. Gokarn, R. Matthew Fesinmeyer, Atul Saluja, Vladimir Razinkov, Susan F. Chase, Thomas M. Laue, and David N. Brems, 2011 PROTEIN SCIENCE,  Mar. 20(3): 580-7
3. Screening of Monoclonal Antibody Formulations Based on High Throughput Thermostability and Viscosity Measurements: Design of Experiment and Statistical Analysis, Feng He, Christopher E. Woods, Egor Trilisky, Keith Bower, Jennifer R. Litowski, Bruce A. Kerwin, Gerald W. Becker, Linda O. Narhi, and Vladimir I. Razinkov  (published online: 2 NOV 2010, JOURNAL OF PHARMACEUTICAL SCIENCE
4. High-throughput dynamic light scattering method for measuring viscosity of concentrated protein solutions.  Feng He, Jennifer Litowski, Linda O. Narhi, David Brems and Vladimir I. Razinkov, ANALYTICAL BIOCHEMISTRY, Volume 399, Issue 1, 1 April 2010, Pages 141-143
5. High Throughput Thermostability Screening of Monoclonal Antibody Formulations. Feng He, Sabine Hogan, Ramil F. Latypov, Linda O. Narhi and Vladimir I. Razinkov, Journal of Pharmaceutical Science, JOURNAL OF PHARMACEUTICAL SCIENCE, 2010 Apr; 99(4):1707-20