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Understand Hazard & Risk

The foundation of a risk-based approach which will allow an organization to use this information to allocate limited resources in the most effective manner.

Inherent Safety In Front End Engineering

Mar 14, 2011
Ian Sutton
The best time to apply the principles of inherent safety is during the early stages of a design. In particular it is at the early stages that the ?Eliminate? option is best applied. For example, in the early stages of one design the process engineers had come up with a system of three knockout...

Using LOPA for Sil Assignment: A Tale of Two Plants

Mar 13, 2011
Michael S. Schmidt
Two plants operated by the same company have ?identical? ammonium nitrate (AN) solution pump installations. Yet the LOPA teams concluded that the safety instrumented functions to protect those pumps needed different safety integrity levels (SILs). Despite the similarity of the installations, the...

Safety Studies for Reformatsky Chemistry In a Meso-Scale Continuous Process System

Mar 13, 2011
Gabriel Loh
The production of fine chemicals and pharmaceuticals has been traditionally achieved via batch processes. More recently, there has been interest in using multiscale (meso- and micro-) reactors for the production of these fine chemicals and pharmaceuticals. These efforts in process intensification...

Incident Investigation – Addressing the Worst That Could Have Happened

Mar 13, 2011
Samuel A. Rodgers
Incident Investigation techniques typically start with a detailed description of the actual consequence and work backward toward the root causes. A lot of time is spent to qualify and quantify the actual consequence so as to appropriately apply resources to prevent recurrence. A frequent outcome of...

Kinetic Modeling of the Reactions Involved in the T2 Explosion

Mar 13, 2011
Ronald J. Willey
The runaway reaction at the chemical preparation facility called T2 laboratories in Jacksonville, Florida on December 19, 2007 is analyzed. The approached involved estimating kinetic parameters based on temperature time traces presented in the CSB final report for ARSST (Advance Reactive System...

Inherently Safer Reactor Design for Complex Reactions Based On Calorimetry Studies

Mar 13, 2011
Alba Lucia Pineda
A number of reactive processes of the agrochemical, fine-chemicals and pharmaceutical industries involve thermally unstable and/or toxic reactants, products or intermediates, for which the chemistry, thermochemistry and thermodynamic properties are barely known. They frequently employ multipurpose...

Improvement of BLEVE Overpressure Method Using Historical Data

Mar 13, 2011
Fei Chen
The current CCPS/TNO's BLEVE (Boiling Liquid Expanding Vapor Explosion) overpressure methodology is derived from that published by Baker in 1975. This methodology assumes isentropic expansion work and uses Baker's graphical method and high-explosive correlation to calculate BLVE energy and...

On the Potential of Mitigating Vapour Cloud Explosions Using Flame Inhibitors

Mar 13, 2011
Kees Van Wingerden
Very few measures are taken to mitigate the possible consequences of vapour cloud explosions. The main attention is given to prediction of the consequences, which is used to consider strengthening structurally or re-locate occupied buildings such as control rooms. However little is undertaken to...

Guidelines for Auditing Process Safety Management Systems, 2nd Edition

February, 2011
This book discusses the fundamental skills, techniques, and tools of auditing, and the characteristics of a good process safety management system. A variety of approaches are given so the reader can select the best methodology for a given audit. This book updates the original CCPS Auditing...

Guidelines for Process Safety in Bioprocess Manufacturing Facilities

November, 2010
This book helps advance process safety in a key area of interest. Currently, no literature exists which is solely dedicated to process safety for the bioprocessing industry. There are texts, guidelines, and standards on biosafety at the laboratory level and for industrial hygiene, but no guidelines...

Explosion at T2 Laboratories

AIChE Webinar
Sep 22, 2010
Robert J. Hall, P.E.

This webinar discusses the CSB investigation and findings related to the explosion and chemical fire at T2 Laboratories, Inc. in December 2007.

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