Quantitative Analysis of Crystalline Materials in Binary Compacts Using Time Domain Spectra of THz Spectroscopy and Density Dependence
- Type: Conference Presentation
- Conference Type:
AIChE Annual Meeting
- Presentation Date:
October 31, 2012
- Skill Level:
The feasibility of Terahertz Time Domain Spectra for quantitative analysis of anhydrous theophylline and the monohydrate in compacts was studied. This study included the analysis of density dependence in quantification accuracy. The effect of density on the Terahertz Time Domain Spectra was demonstrated. An improvement in model performance was demonstrated when density was undertaken into consideration.