SBE Courses
SBE is considering offering the following Frontier Tutorial during the AIChE Annual Meeting this year. If you are interested, please email us at bio@aiche.org for more information.
Discovery and Early Stage Development of Protein Therapeutics
What you will learn:
- Quantitative pharmacology of protein biopharmaceuticals
- Directed evolution of enzymes
- Directed evolution methods for engineering the binding properties of antibodies
- Engineering microbial expression systems for protein therapeutics
Who should attend:
All those interested in learning about the discovery and development of protein therapeutics. This course provides enough background to appeal to the novice while bringing cutting-edge research methods to the expert. Research managers, engineers, biochemists, scientists and students who are interested in learning about various technical and practical aspects of Protein Therapeutics should attend.
Course Instructors:
George Georgiou is the J.C. Walter Professor at the University of Texas, Austin. This year he was elected into the National Academy of Engineering. He is also a fellow of American Association for the Advancement of Science, the American Academy of Microbiology, and the American Institute for Medical and Biological Engineering. He serves on the editorial board of the J. Biotechnology, Biotechnology and Bioengineering, and Protein Expression and Purification, among others. His research focuses on protein engineering, molecular evolution of improved antibodies and enzymes, protein folding and expression, and engineering of bacterial cell surfaces.
K. Dane Wittrup is the J.R. Mares Professor at Massachusetts Institute of Technology. He is a fellow of the American Institute for Biomedical and Biological Engineering. His current research focus is molecular bioengineering, protein engineering, and therapeutic protein biotechnology. His lab develops protein engineering technology and applies it to the discovery of new biopharmaceuticals. In particular, yeast surface display is used for the directed evolution of protein expression stability, affinity, and specificity. A specific focus is on the development of anti-cancer drugs, with quantitative studies of cellular-level pharmacokinetics and pharmacodynamics.